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Fig. 18.1(TE Art) Pineal gland Pituitary gland Hypothalamus Thyroid gland Thymus Adrenal glands Pancreas Testes Ovaries Gonads Parathyroid glands
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Fig. 18.3(TE Art) Endocrine system Endocrine cells Hormone in bloodstream Nervous system
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Fig. 18.1(TE Art) Pineal gland Pituitary gland Hypothalamus Thyroid gland Thymus Adrenal glands Pancreas Testes Ovaries Gonads Parathyroid glands
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hypothalamus Pituitary gland
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Hypothalamo- hypophyseal tract Stalk Neurohypophysis Posterior lobe Pars tuberalis Anterior lobe Adenohypophysis Pituitary gland
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Fig. 18.4a(TE Art) Hypothalamohypophyseal tract Posterior lobe Paraventricular nucleus Supraoptic nucleus Oxytocin ADH Anterior lobe Oxytocin = uterus & mammary glands Antidiuretic hormone = kidneys
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Superior hypophyseal artery Posterior pituitary Anterior pituitary Releasing hormones “go and do something” hormones
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Fig. 18.6(TE Art) Growth hormone ACTH TSH prolactin Liver Fat, muscle, bone LH FSH TRH GnRH CRH Hypothalamus Adrenal cortex OvaryTestis Thyroid Mammary gland IGF
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Fig. 18.10a(TE Art) Adrenal gland Kidney Adrenal cortex Adrenal medulla epinephrine norepinephrine
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Adrenal gland Kidney Adrenal cortex mineralcorticoids glucocorticoids sex steroids Adrenal medulla Aldosterone (mineralcorticoid): kidney = retain Na, excrete K (water retained, BP) Cortisol (glucocorticoid): fat & protein breakdown, glucose synthesis, fatty acid & glucose release into blood, help body adapt to stress, repair damaged tissues Dehydroepiandrosterone (DHEA): weak testosterone = libido, 2 nd sex characteristics
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Cushing’s Syndrome – adrenal cortex – hypersecretion of cortisol
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Thyroid Thymus Trachea
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Thyroid gland Follicular cells: T3 & T4 – increase metabolic rate C cells: calcitonin – inhibits osteoclasts…..
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Pharynx Thyroid gland Esophagus Parathyroid glands Trachea Detect low calcium Secrete PTH increase Ca absorption inhibits Ca excretion stimulates osteoclasts Posterior view
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Fig. 18.11a(TE Art) Bile duct Duodenum Head of pancreas Pancreatic ducts Body of pancreas Tail of pancreas
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Pancreatic islet cell-- insulin cell -- somatostatin cell -- glucagon Insulin: controls glucose transport into cells Diabetes Type I: low or no B-cells, no insulin Diabetes Type II: insulin insensitivity (receptor) hyperglycemia emaciation atherosclerosis (fatty deposits) ketoacidosis (low blood pH) = coma, death
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Fig. 18.1(TE Art) Pineal gland Pituitary gland Hypothalamus Thyroid gland Thymus Adrenal glands Pancreas Testes Ovaries Gonads Parathyroid glands
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