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Is the ANS a division of the CNS or PNS?
2. Is there a sensory division of the ANS? 3. Name this structure 4. What is contained in this structure? 5. During a sympathetic response, what happens to the following organs? Pupils Sweat glands Blood vessels to muscles Bronchi Adrenal medulla
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Endocrine System overview of endocrine system how it works
hypothalamus and pituitary gland adrenal gland thyroid and parathyroid pancreas
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Fig. 18.1(TE Art) Hypothalamus Pituitary gland Thyroid gland Pineal
Parathyroid glands Thymus Adrenal glands Pancreas Gonads Ovaries Testes
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Fig. 18.3(TE Art) Nervous system Endocrine system Endocrine cells
Hormone in bloodstream Endocrine system
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Fig. 18.1(TE Art) Hypothalamus Pituitary gland Thyroid gland
Parathyroid glands Adrenal glands Pancreas
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hypothalamus pituitary gland
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Pituitary gland Pars tuberalis Hypothalamohypophysial tract Anterior
lobe Stalk Posterior lobe Anterior pituitary (Adenohypophysis) = pars tuberalis + anterior lobe Posterior pituitary (Neurohypophysis) = stalk + hypothalamohypophysial tract + posterior lobe
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Fig. 18.4a(TE Art) Oxytocin = uterus & mammary glands…
Paraventricular nucleus Supraoptic nucleus Hypothalamohypophysial tract Anterior lobe Posterior lobe Oxytocin ADH Oxytocin = uterus & mammary glands… Antidiuretic hormone = kidneys
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Superior hypophyseal artery
Releasing hormones Releasing hormones Travel through stalk to the Anterior pituitary via portal venules “go and do something” hormones Anterior pituitary
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Fig. 18.6(TE Art) Hypothalamus TRH GnRH CRH prolactin Growth hormone
Liver IGF Mammary gland Fat, muscle, bone TSH LH FSH ACTH Thyroid Adrenal cortex Testis Ovary
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hormone secreting cells capillaries
Anterior pituitary hormone secreting cells capillaries Posterior pituitary unmyelinated nerve fibers glial cells (pituicytes) capillaries
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Pituitary tumors – headaches, visual disturbances, hormonal issues
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Adrenal glands
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Fig. 18.10a(TE Art) Adrenal gland Kidney Adrenal medulla epinephrine
norepinephrine Adrenal cortex
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Adrenal medulla Adrenal cortex mineral-corticoids glucocorticoids
sex steroids Aldosterone (mineralocorticoid): kidney = retain Na, excrete K (water retained, BP) Cortisol (glucocorticoid): fat & protein breakdown, glucose synthesis, fatty acid & glucose release into blood, help body adapt to stress, repair damaged tissues (Cushing’s Syndrome – adrenal cortex – hypersecretion of cortisol) Dehydroepiandrosterone (DHEA): weak testosterone = libido, 2nd sex characteristics
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Thyroid Hyoid bone Thyroid cartilage
Follicular cells: T3 & T4 – increase metabolic rate C cells: calcitonin – inhibits osteoclasts…..
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Goiter: enlargement of thyroid
soil & water deficient in iodine enlargement of thyroid gland Graves disease – toxic goiter Recurrent laryngeal nerve innervates larynx can get damaged during a thyroidectomy
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epiglottis Parathyroid glands Esophagus
Detect low calcium Parathyroid glands Secrete PTH increase Ca absorption inhibits Ca excretion stimulates osteoclasts Esophagus Posterior view
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Body of pancreas Duodenum Pancreas = endocrine + exocrine organ
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Pancreatic islet b cell-- insulin a cell -- glucagon
Insulin: controls glucose transport into cells Diabetes Type I: low or no B-cells, no insulin Diabetes Type II: insulin insensitivity (receptor) hyperglycemia emaciation atherosclerosis (fatty deposits) ketoacidosis (low blood pH) = coma, death b cell-- insulin a cell -- glucagon d cell -- somatostatin
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Fig. 18.1(TE Art) Hypothalamus Pituitary gland Thyroid gland Pineal
Parathyroid glands Thymus Adrenal glands Pancreas Gonads Ovaries Testes
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