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APh161 - Lecture 11: The Cytoskeleton is Always Under Construction Rob Phillips California Institute of Technology Mullins et al.

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Presentation on theme: "APh161 - Lecture 11: The Cytoskeleton is Always Under Construction Rob Phillips California Institute of Technology Mullins et al."— Presentation transcript:

1 APh161 - Lecture 11: The Cytoskeleton is Always Under Construction Rob Phillips California Institute of Technology Mullins et al.

2 Polymerization Processes 1: Tobacco Mosaic Virus Caspar

3 A reminder on the cytoskeleton

4 Cytoskeletal Action During Cell Division

5 Cytoskeleton Mediated Mitosis Show the movies in the Lecture 11 directory – see http://www.bio.unc.edu/faculty/salmon/lab/mitosis/mitosismovies.html

6 Cell Division in Bacteria Petra Levin FtsZ rings during division

7 Actin Polymerization Rate in vitro

8 Actin and its Partners

9 Life at the Leading Edge

10 Microtubule Dynamics: Part of the Polymerization Puzzle

11 Microtubule Dynamics In Vitro Show Borisy movies, http://www.borisylab.nwu.edu/pages/supplemental/treadmill.html Flyvbjerg et al., 1996 Catastrophe rate vs. growth rate

12 The Story of ParM (Dyche Mullins et al.)

13 ParM Length Distribution Mullins et al., Science 2004

14 Polymerization of Pyrene Labeled Actin Lim et al., Science 2004


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