1. A Little Lite Goes A Long Way® The Litebook Company Ltd. www.litebook.com Presented by: Larry Pederson, Founder September 2007 The Light You Need … Every Day® www.litebook.com

2. The Litebook® Elite™ A New Generation of Light Therapy™

3. We live in a light-deprived world...

4. …And we are paying for it with our health.

5. Why we are ‘light deprived’  Work indoors  Play indoors  Travel indoors  Many now believe that sunlight = bad  ozone layer depletion = > UV radiation  > risk of skin cancer  Avg. exposure 57 mins/day in sunny San Diego! (Dr. Kripke, UCSD 2004)

6. Are your customers ‘light deprived’…? Are they:  Office worker  Stay-at-home mom  Elderly  Teen  Shift-worker  Business traveler  Anyone…??  You…??

7. What is S.A.D.?  DSM-IV Definition:  Major depression indications, plus:  Relationship between onset of major depressive episodes and particular time of year.  Full remissions also occur at characteristic time of year.  Seasonal depressive episodes substantially outnumber non-seasonal episodes, for > 2 years.

8. What is ‘Winter Blues’?  Sub-syndromal Seasonal Affective Disorder  Similar but milder indications  Not ‘clinically depressed’ -- do not typically require Rx  Often mis-diagnosed or non-diagnosed  Seasonal component as with SAD

9. SAD Facts:  Incidence in Canada:  2-5% (est.)  ‘Winter Blues’ - additional 25% (NMHA’02)  Increases with latitude  Gender: 75% Female vs. 25% Male  Age: Typical onset is early 20’s - mid-40’s

10. SAD Symptoms (Seasonally):  Depressed mood most of the day, nearly every day.  Marked diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day.  Decreased energy  Decreased self-esteem  Increased appetite and/or weight  Carbohydrate craving  Hypersomnia  Difficulty concentrating  Irritability  Social withdrawal  Decreased libido

11. Treatment Options for SAD:  Medications:  SSRI’s (Prozac, Zoloft, etc.)  Wellbutrin XL – newly approved by FDA  Light therapy:  Daily early morning scheduled exposure to bright artificial light  Response rate: range 60% - 90%; avg. 65%  Combined light & medication

12. Light Therapy for SAD:  Long considered ‘alternative therapy’  Now becoming preferred treatment option with psychiatrists, GPs and psychologists  Patient-driven -- many w/ SAD don’t view themselves as having psychiatric illness = do not want to take Rx meds  Some patients do well on Rx; some don’t  Many do better on light therapy than on Rx  FDA review: data on light therapy for SAD is “overwhelming and irrefutable”

13. Other Indications for Light Therapy:  Shift-work  Jet lag  Sleep Disorders –  Delayed Phase Sleep Disorder (DPSD)  Advanced Phase Sleep Disorder (APSD)  Fatigue Management (CFS, MS, Chemo pts.)  Performance enhancement – athletes, execs  ‘Baby Blues’ & Post-partum depression

14. Contraindications for Light Therapy:  No evidence of danger using 10K light boxes – or The Litebook (in market since 2001; 46 countries)  Older patients w/ history of eye problems (cataracts, macular degeneration, diabetes w/ retinopathy) should have eye exam or consult eye doc before using  Corrective laser eye surgery in past 30 days  Currently taking any Rx w/ photosensitivity profile -- UV triggers reaction (Litebook Elite emits NO UV).  Bi-polar on antidepressants could become manic, trigger hypomania = use under careful medical supervision  Recommend consult with MD or ophthalmologist prior to using light therapy

15. Why does Light Therapy Work?  No definitive answer yet  Bright light does impact melatonin and serotonin levels  Melatonin produced in response to ‘low light’ or ‘no light’  Critical discovery (1979): bright light suppresses melatonin  Critical discovery (2001): blue wavelength light most effective for melatonin suppression

16. How Light Therapy Works  Mechanism: Bright light strikes retinal non-visual photoreceptor (melanopsin)  optic nerve  Suprachiasmatic nucleus (SCN)  pineal gland  melatonin suppression  phase shift

17. Melatonin Suppression Curve Primary = 464nm (blue) Secondary = 550nm (green)

18. Litebook’s white LEDs = Efficiency 2

19. Sunlight & The Litebook®

20. Traditional Light therapy  Litebook ‘Knock-offs’

21. The Litebook® Elite™

22. What Makes The Litebook® Elite™ Unique: Our Advantages:  Clinically proven for SAD  Patented LED technology  Completely portable  Rechargeable lithium-Ion battery (2 hrs fully charged)  Timer: 15-30-45-60 mins.  Compact: 12.5cm x 12.5cm x 2.5cm  Lightweight – 327g  Low power – 2.4 Watts  Low heat  UV-free, long-lasting white LEDs  Custom Fresnel lens/diffusion system  EU Medical Device Certified - CE0086  ISO 9001 & ISO 13485 certified

23. Litebook Leads in Research:  SAD: Pub. Aug 07 – BioMed Central online journal Canada: UBC; McGill; Royal Ottawa Hospital USA: Yale University Europe: U of Groningen, The Netherlands  Litebook + Exercise = Body Fat Reduction:  Pub. July07 – Journal of Obesity Vol. 15, No. 7  Toronto Western Hospital  Shift-work: Canada: McGill & Montreal Police (COMPLETED) UK: U of Surrey - North Sea drilling platform (COMPLETED)  Teens with ADHD: U of Maryland – Baltimore, MD (ONGOING)  Anxiety Disorder: U of South Carolina – Columbia, SC (ONGOING)  Fatigue Mgmt in Chemo Patients: UC San Diego (ONGOING)

24. Litebook’s Scientific Advisory Board:  Dr. Raymond Lam M.D.  Director, Mood Disorders Clinic, University of British Columbia  Dr. Dan Oren M.D.  Associate Clinical Professor of Psychiatry, Yale University  Dr. Siegfried Kasper M.D.  Professor & Chair, Dept. of Gen. Psychiatry, U of Vienna  Dr. Oscar Cuzzani M.D.  Ophthalmologist; Retinal Surgeon, Researcher (Light Toxicity)  Dr. James Maas Ph.D.  Professor & Past Chair, Dept. of Psychology, Cornell U. (cont’d)

25. Litebook’s Scientific Advisory Board:  Dr. Carlan Silha Ph.D.  Systems & Engineering Mgmt; Lt. Col USAF (Ret.); Retired Boeing  Mr. Cal Koskowich P.Eng.  National Research Council of Canada  Mr. Larry Crabb  Col. RCAF (Ret.); ISO Compliance & Business Development Consultant

26. Litebook Usage:

27. The Litebook® Elite™ Packaging - Strong shelf appeal - Every unit has ‘demo’ feature - Bilingual packaging – Canada/EU

28. Litebook Summary:  A new generation of light therapy  Patented white LEDs = safe, long life, low power  Blue wavelength peak = shorter treatment time  Feature-rich, user-friendly product design  Clinically proven  World-class Scientific Advisory Board  Industry leading 60-day money-back guarantee  Low return rate: < 0.5%  2-year warranty

29. A Little Lite Goes A Long Way® The Litebook Company Ltd. www.litebook.com Presented by: Larry Pederson, Founder September 2007 The Light You Need … Every Day® www.litebook.com