1. Microelectrode Recording Using the NEXDRIVE by ign

2. Microelectrode Recording Adjust NEXDRIVE base Assemble the NEXDRIVE Insert the cannulae Insert the microelectrode Additional tracks: –Perform a parallel track –Using the offset positioner Place the DBS lead

3. Adjust NEXDRIVE base Loosen locking screws Adjust Z-stage to set drive to target depth reported by IGS Tighten locking screws Loosen Lock Turn

4. NEXDRIVE Assembly Remove alignment adapter Insert Center multi- lumen insert Attach micro-drive Note: be sure drive is set to starting depth Multi-lumen Insert

5. Cannulae insertion Insert stylet through passing cannula Attach collet to passing cannula Pass cannula/collet combo into drive Remove Stylet Insert microelectrode cannula Note: be sure drive is set to starting depth

6. Microelectrode insertion Retract microelectrode within sheath Pass microelectrode through cannula Advance electrode Connect recording system cables Note: be sure drive is set to starting depth

7. Microelectrode Recording

8. Parallel Tracts Retract drive to starting point Retract and remove microelectrode & collet Remove cannula & re-insert through offset

9. Offset Positioner Retract drive to starting point Remove microelectrode Remove cannulae Remove drive and drive base Remove center multi-lumen insert Choose direction for offset Insert offset positioner Re-assemble drive and cannula

10. Possible Tracks Center Positioner 3mm offset at “B” 3mm offset at “G” Center Positioner at 45°

11. Lead Placement Set drive to desired target depth Remove microelectrode and spacer cannula Calibrate lead with calibration tube Remove calibration tube and insert lead