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Fig. 4. Visual and RPE phagocytic function in Best1Y227N mice.

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Presentation on theme: "Fig. 4. Visual and RPE phagocytic function in Best1Y227N mice."— Presentation transcript:

1 Fig. 4. Visual and RPE phagocytic function in Best1Y227N mice.
Visual and RPE phagocytic function in Best1Y227N mice. (A–D) Scotopic and photopic electroretinogram (ERG) analysis of dark-adapted (A) and light-adapted (B) B6/J +/+, +/N and N/N mice with stimulus intensities ranging from −4–1.5 and −2–1.5 log cd*s/m2, respectively. (C) Overlay of indicated traces under scotopic and photopic conditions extracted from A and B. (D) Measurements of standing potential changes were performed in B6/J +/+, +/N and N/N mice using a 10 min light pulse with a fixed intensity of 0.6 log cd*s/m2 in fully dark-adapted animals. Shown are traces of 11 min duration using direct-current signal amplification. Arrows indicate beginning and end of light exposure. (E) Visual acuity of B6/J +/+, +/N and N/N mice was analyzed by a virtual optomotor system. As indicated, mice of two different age groups were tested five times on subsequent days for acuity of the right and left eye. Data are given as mean acuity of two eyes per mouse. N=number of animals analyzed. Andrea Milenkovic et al. Biology Open 2019;8:bio041335 © Published by The Company of Biologists Ltd

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