1. PVM candidates with a signal peptide and/or at least one transmembrane domain.
PVM candidates with a signal peptide and/or at least one transmembrane domain. Data corresponding to PVM or PV localization of candidate proteins in P. berghei and P. falciparum determined on the basis of this work and published studies that used electron and/or fluorescence microscopy techniques for protein localization are indicated. Proteins that showed at least partial PVM localization during blood and/or liver stage development in P. berghei or P. falciparum are indicated in green, while proteins with at least partial PV localization and no further PVM localization are shown in blue. Candidate proteins analyzed in this study are highlighted in bold. P. falciparum orthologs were identified in and, in some cases, synteny was used as a further indicator to support orthology (indicated by asterisks). Candidates are ordered by increasing average P values. For details regarding localizations (including references) see Table S2. ID, identifier; SP, signal peptide. TM, number of transmembrane domains.
Cilly Bernardette Schnider et al. mSphere 2018; doi: /mSphere