1. Categorization of the top 200 N
Categorization of the top 200 N. gonorrhoeae genes expressed during natural infection in men.
Categorization of the top 200 N. gonorrhoeae genes expressed during natural infection in men. Expression of gonococcal genes in 6 infected men was averaged, and the top 200 genes were categorized based on characteristics indicated for N. gonorrhoeae strain FA1090 available in NCBI. Categories are shown on the y axis, and the ratio of enrichment (% of genes of a given functional category in RNA-seq data set/% of genes assigned to that functional category in whole gonococcal genome) is shown on the x axis. For clarity, ribosomal protein, tRNA, and rRNA genes were removed. Asterisks indicate that enrichment was significant (P ≤ 0.05) by Fisher’s exact test.
Kathleen Nudel et al. mSphere 2018; doi: /mSphereDirect