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1. What does it mean for something to be “genetically engineered” (or genetically modified or genetically manipulated)? 2. Give an actual example of something.

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Presentation on theme: "1. What does it mean for something to be “genetically engineered” (or genetically modified or genetically manipulated)? 2. Give an actual example of something."— Presentation transcript:

1 1. What does it mean for something to be “genetically engineered” (or genetically modified or genetically manipulated)? 2. Give an actual example of something that you know of that is genetically modified (GMO=genetically modified organism).  If you know of something.

2 1. Genetic engineering is when…
Genetic engineering is when the DNA of an organism is manipulated or changed by adding foreign DNA into the organism's DNA by humans for a specific purpose.

3 2. Examples of GMOs Plants
Tomatoes (Flavr Savr Tomatoes) – resistance to colder temperatures, ripen more slowly Soybeans, cotton, corn: resistance to pests and herbicides Rice (“Golden Rice”) (added beta-carotene gene from corn) – source of Vitamin A Banana vaccines – humans eats, build up immune system Venomous cabbage (venom from scorpions) – kill caterpillars/pests Animals Eggs (from hen) – produce proteins to help fight against cancer & diseases Atlantic salmon (gene from Chinook salmon) – grow faster Cows that release less methane – contribute less to greenhouse effect GloFish – zebrafish with fluorescent gene to detect environmental pollutants Glow-in-the-dark cats (gene from jellyfish that makes fluorescent) – AIDS research

4 Banana vaccines: Glofish: Glow in the dark cats: Venomous cabbage:

5 Cloning The new (offspring) organism is genetically identical to the donor (parent) organism. Example: Dolly the sheep – first mammal to be cloned Take nucleus from one of “parent’s” cells and implant it into the egg that has had its own nucleus removed  electricity or chemicals to make cell divide  then implant into uterus Other examples: cat, dog, tadpole, rat, horse, cattle, camel, water buffalo, carp, etc.

6 Have humans been cloned?
Despite several highly publicized claims, human cloning still appears to be fiction. There currently is no solid scientific evidence that anyone has cloned human embryos. In 1998, scientists in South Korea claimed to have successfully cloned a human embryo, but said the experiment was interrupted very early when the clone was just a group of four cells. In 2002, Clonaid, part of a religious group that believes humans were created by extraterrestrials, held a news conference to announce the birth of what it claimed to be the first cloned human, a girl named Eve. However, despite repeated requests by the research community and the news media, Clonaid never provided any evidence to confirm the existence of this clone or the other 12 human clones it purportedly created. In 2004, a group led by Woo-Suk Hwang of Seoul National University in South Korea published a paper in the journal Science in which it claimed to have created a cloned human embryo in a test tube. However, an independent scientific committee later found no proof to support the claim and, in January 2006, Science announced that Hwang's paper had been retracted. From a technical perspective, cloning humans and other primates is more difficult than in other mammals. One reason is that two proteins essential to cell division, known as spindle proteins, are located very close to the chromosomes in primate eggs. Consequently, removal of the egg's nucleus to make room for the donor nucleus also removes the spindle proteins, interfering with cell division. In other mammals, such as cats, rabbits and mice, the two spindle proteins are spread throughout the egg. So, removal of the egg's nucleus does not result in loss of spindle proteins. In addition, some dyes and the ultraviolet light used to remove the egg's nucleus can damage the primate cell and prevent it from growing.

7 Remember: DNA replication Transcription Translation
DNA  DNA (A, T, G, C) Transcription DNA  RNA (A, U, G, C) Translation RNA  protein (amino acids – codon chart)


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