1. Heat maps of stress- and development-related genes differentially expressed between the osdR mutant and its parent, S. coelicolor M145.
Heat maps of stress- and development-related genes differentially expressed between the osdR mutant and its parent, S. coelicolor M145. Transcription patterns (expressed as fold changes between the osdR mutant and the wild type) are presented for genes close to osdRK (A), stress-related genes (B), anaerobic-growth-related genes (C), and developmental genes (D). RNA was isolated from MM agar during vegetative growth (24 h), vegetative/aerial growth (30 h), aerial growth (36 h), aerial growth/early sporulation (42 h), and sporulation (54 h). Blue indicates downregulation (<0.5) and red indicates upregulation (>2.0) in the mutant; intermediate fold changes are represented in white. See Table S4 in the supplemental material. db #, database locus tag.
Mia Urem et al. mSystems 2016; doi: /mSystems