1. An Introduction to the NIHR programmes
Professor Tom Walley
9 February 2012

2. Decline in clinical research in surgery
Service demands
Lack of equipoise
Lack of expertise in clinical trials
Easier ways to keep RAE/university happy (consent, regulation of clinical trials etc)
But:
Lack of information to inform practice
Professional (eg RCS, ASGBI) enthusiasm for more clinical research

3. Call for Applied Research in Surgery
Application forms available on 23 February. Closing date 25 May 2012
Particular interests
Surgical procedures
Alternatives to surgery (surgical comparators)
Patient safety/experiences
Devices
Organisation of services

4. What is applied research?
Research with the capacity to improve patient outcomes and NHS services
Clinical research (not only trials)
Not
Discovery science
Animal
See remit of participating programmes - if in doubt ask

5. Participating programmes
CCF programmes
Invention for Innovation Programme (i4i)
Programme Grants for Applied Research Programme
Programme Development Grants
Research for Patient Benefit Programme
NETS programmes
HTA
EME
HS&DR

6. The NIHR Health Research System
Faculty
Investigators & Senior Investigators
Associates
Trainees
Universities
Infrastructure
Research
Clinical Research Networks
NHS Trusts
Research Projects & Programmes
Patients & Public
Clinical Research Facilities, Centres & Units
Research Schools
Make reference to CCF as the other funder of NIHR research programmes
Research Governance Systems
Research Information Systems
Systems

7. National Institute for Health Research
INVENTION
EVALUATION
ADOPTION
DIFFUSION
Basic Research
Development Pathway Funding
MRC
Efficacy & Mechanism Evaluation
Invention for Innovation
Biomedical Research Centres
This pathway covers the full range of interventions - pharmaceuticals, biologicals, biotechnologies, procedures, therapies and practices - for the full range of health and health care delivery - prevention, detection, diagnosis, prognosis, treatment, care.
Biomedical Research Units
Patient Safety and Quality Research Centres
Research for Innovation, Speculation & Creativity
Research for Patient Benefit
Health Services & Delivery Research
National Institute for Health Research
Programme Grants for Applied Research
Public Health Research
Health Technology Assessment
Collabs for Ldrshp in Appl Hlth Res and Care
Ctr for Reviews & Dissemination, Cochrane, TARs
NHS Purchasing & Supplies Agency
Centre for Evidence-based Purchasing
National Institute for Health & Clinical Excellence
Guidance on Health & Healthcare
NHS Evidence
Access to Evidence
NHS Institute for Innovation & Improvement
Support for the NHS
Strategic Health Authorities
Duty of Innovation
Primary Care Trusts
Healthcare Commissioning
NHS Providers
Patient Care

8. Clinical Research Networks
NIHR as a system
Clinical Research Networks
Joint calls
Facilitating researchers, speeding review
Transfers between NIHR programmes
Active collaboration between programmes
Directors' meetings
Meeting with networks
CCF
i4i
PGfAR
RfPB
NETSCC
HS&DR
HTA
EME

9. Which programme? Visit the market place
EME – exploratory trials, less pragmatic, phase 2-3, efficacy, mechanisms if possible?
HTA – systematic reviews, large multicentre pragmatic trials or other studies (phase 3-4), effectiveness in the NHS
HS&DR – organisational, patient experience, qualitative or other
i4i - translation of bright ideas for new high-tech products into methods of prevention, diagnosis and treatment
PGfAR- £2m for up to 5 years, awards made to NHS bodies
RfPB – max £250k for up to three years

10. Themed Call on Research in Surgery
Watch the website for dates
Engage collaborators, CTUs, RDS as soon as you can
Closing date for outlines (vary by programme, not RfPB)
May 25th
Closing dates for fulls (vary by programme)
October
Final funding decisions
March 2013

11. Thank you
9 February 2012