1. Is the Myofibrillarlytic Myocyte a Forme Fruste Apoptotic Myocyte?
Navneet Narula, MD, Jagat Narula, MD, PhD, Paul J. Zhang, MD, Nezam Haider, PhD, Puthiyaveettil N. Raghunath, PhD, Robin Brittin, MS, Joseph H. Gorman, MD, Robert C. Gorman, MD, John E. Tomaszewski, MD 
The Annals of Thoracic Surgery 
Volume 79, Issue 4, Pages (April 2005)
DOI: /j.athoracsur
Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

2. Fig 1
Immunohistochemical characterization of myofibrillarlytic cells. (A) Myofibrillarlytic cells are observed in an ischemic cardiomyopathic myocardial sample with vacuolated cytoplasm (hematoxylin & eosin, original magnification ×20). (B) Although these cells stain modestly for the upregulation caspase-3 (Anticaspase-3 antibody, immunoperoxidase, original magnification ×20), these cells stain intensely for the (C) antiapoptotic protein, Bcl2 (anti-Bcl-2 antibody; immunoperoxidase, original magnification ×20) and (D) BCL-XL (anti-BCL-XL antibody; immunoperoxidase, original magnification ×20).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

3. Fig 2
Immunohistochemical characterization of myofibrillarlytic cells. Staining of the myofibrillarlytic cells with (A) TUNEL, (B) ISOL, (C) PCNA, and (D) Ki67 suggests lack of completion of apoptotic process. TUNEL-positivity probably represents myocyte repair or hypertrophy. The staining has been performed in serial sections. As shown, the myofibrillarlytic cell nuclei are positive for TUNEL and PCNA, and negative for ISOL and Ki67 (immunoperoxidase, original magnification ×20).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions