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Rosai-Dorfman Disease of Right Atrium Mimicking Myxoma

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Presentation on theme: "Rosai-Dorfman Disease of Right Atrium Mimicking Myxoma"— Presentation transcript:

1 Rosai-Dorfman Disease of Right Atrium Mimicking Myxoma
Surendra Nath Khanna, MS, MCh, Krishna Subramony Iyer, MS, MCh, Mathews Paul, BS, S. Radhakrishnan, MD, DM, Arun K. Rathi, BS  The Annals of Thoracic Surgery  Volume 103, Issue 5, Pages e443-e445 (May 2017) DOI: /j.athoracsur Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 (A) Transesophageal echocardiography image showing large mass in the right atrium (RA), causing right atrial outflow obstruction. (LV = left ventricle; RV = right ventricle.) (B) Intraoperative photograph of right atrial mass. (IVC = inferior vena cava; SVC = superior vena cava.) The Annals of Thoracic Surgery  , e443-e445DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 (A) Stained section reveals a lesion composed of histiocytes with abundant cytoplasm and arranged in sheets and vague lobules. (Hematoxylin and eosin, original magnification ×100.) (B) Higher magnification show majority of the histiocytes show plasma cells, mature lymphocytes, and red blood cells within the cytoplasm indicating emperipolesis. (Hematoxylin and eosin, original magnification ×400.) The Annals of Thoracic Surgery  , e443-e445DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Histiocytic cells are positive for (A) CD68 and (B) S-100 (CD68 and S-100 immunostain; original magnification ×400), and negative for CD1a (not shown), confirming the diagnosis of Rosai-Dorfman disease. The Annals of Thoracic Surgery  , e443-e445DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions


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