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Mutation Analysis of the Rearranged Immunoglobulin Heavy Chain Genes of Marginal Zone Cell Lymphomas Indicates an Origin From Different Marginal Zone B.

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Presentation on theme: "Mutation Analysis of the Rearranged Immunoglobulin Heavy Chain Genes of Marginal Zone Cell Lymphomas Indicates an Origin From Different Marginal Zone B."— Presentation transcript:

1 Mutation Analysis of the Rearranged Immunoglobulin Heavy Chain Genes of Marginal Zone Cell Lymphomas Indicates an Origin From Different Marginal Zone B Lymphocyte Subsets by A. Tierens, J. Delabie, S. Pittaluga, A. Driessen, and C. DeWolf-Peeters Blood Volume 91(7): April 1, 1998 ©1998 by American Society of Hematology

2 Deduced protein sequences of the rearranged V h genes of the cases of marginal zone lymphomas.
Deduced protein sequences of the rearranged V h genes of the cases of marginal zone lymphomas. Lowercase, replacement mutations with regard to the germline sequences. FR, framework; CDR, complementarity determining region. CDR regions are underlined. A. Tierens et al. Blood 1998;91: ©1998 by American Society of Hematology


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