1. Possible explanation for the strong correlation between mRNA folding (mF) strength and protein abundance (PA).
Possible explanation for the strong correlation between mRNA folding (mF) strength and protein abundance (PA). (A) Correlation between mF strength with ribosomal density (RD) and with the product of RD and mRNA levels. (B) Correlation between the mF strength of different segments of the coding sequence and PA (similar results were obtained for correlation with mean RD, and mean RD × mean mRNA levels—see supplementary Figs S1–S4 online). (C) There is no correlation between mF strength and mRNA half‐life (HL). (D) An illustration of a possible explanation for the relation between mF strength and PA.
Hadas Zur, and Tamir Tuller EMBO Rep. 2012;13:
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