1. Review of Protein Synthesis

2. Fig. 17-3 TRANSCRIPTION TRANSLATION DNA mRNA Ribosome Polypeptide (a) Bacterial cell Nuclear envelope TRANSCRIPTION RNA PROCESSING Pre-mRNA DNA mRNA TRANSLATION Ribosome Polypeptide (b) Eukaryotic cell

3. Fig. 17-3a-1 TRANSCRIPTION DNA mRNA (a) Bacterial cell

4. Fig. 17-3a-2 (a) Bacterial cell TRANSCRIPTION DNA mRNA TRANSLATION Ribosome Polypeptide

5. Fig. 17-3b-1 (b) Eukaryotic cell TRANSCRIPTION Nuclear envelope DNA Pre-mRNA

6. Fig. 17-3b-2 (b) Eukaryotic cell TRANSCRIPTION Nuclear envelope DNA Pre-mRNA RNA PROCESSING mRNA

7. Fig. 17-3b-3 (b) Eukaryotic cell TRANSCRIPTION Nuclear envelope DNA Pre-mRNA RNA PROCESSING mRNA TRANSLATION Ribosome Polypeptide

8. Fig. 17-4 DNA molecule Gene 1 Gene 2 Gene 3 DNA template strand TRANSCRIPTION TRANSLATION mRNA Protein Codon Amino acid

9. Fig. 17-5 Second mRNA base First mRNA base (5 end of codon) Third mRNA base (3 end of codon)

10. Fig. 17-10 Pre-mRNA mRNA Coding segment Introns cut out and exons spliced together 5 Cap Exon Intron 5 1 30 31104 ExonIntron 105 Exon 146 3 Poly-A tail 5 Cap 5 UTR3 UTR 1 146

11. Fig. 17-11-1 RNA transcript (pre-mRNA) Exon 1Exon 2Intron Protein snRNA snRNPs Other proteins 5

12. Fig. 17-11-2 RNA transcript (pre-mRNA) Exon 1Exon 2Intron Protein snRNA snRNPs Other proteins 5 5 Spliceosome

13. Fig. 17-11-3 RNA transcript (pre-mRNA) Exon 1Exon 2Intron Protein snRNA snRNPs Other proteins 5 5 Spliceosome components Cut-out intron mRNA Exon 1 Exon 2 5

14. Fig. 17-12 Gene DNA Exon 1Exon 2 Exon 3 Intron Transcription RNA processing Translation Domain 2 Domain 3 Domain 1 Polypeptide

15. Fig. 17-23a Wild type 3 DNA template strand 3 3 5 5 5 mRNA Protein Amino end Stop Carboxyl end A instead of G 3 3 3 U instead of C 5 5 5 Stop Silent (no effect on amino acid sequence)

16. Fig. 17-23b Wild type DNA template strand 3 5 mRNA Protein 5 Amino end Stop Carboxyl end 5 3 3 T instead of C A instead of G 3 3 3 5 5 5 Stop Missense