1. AJKD Atlas of Renal Pathology: IgG4-Related Tubulointerstitial Nephritis 
Behzad Najafian, MD, Agnes B. Fogo, MD, Mark A. Lusco, MD, Charles E. Alpers, MD 
American Journal of Kidney Diseases 
Volume 69, Issue 4, Pages e19-e20 (April 2017)
DOI: /j.ajkd
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

2. Figure 1
IgG4-related TIN with abundant plasma cells (Jones silver stain). The presence of nests of inflammatory cells surrounded by collagen bundles (bird’s eye pattern) is a typical finding. There might be frequent interstitial eosinophils as seen in this case (upper right).
American Journal of Kidney Diseases  , e19-e20DOI: ( /j.ajkd )
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

3. Figure 2
IgG4-related TIN with storiform fibrosis where fibroblasts and inflammatory cells arrange in pattern resembling spokes of a cartwheel (Jones silver stain).
American Journal of Kidney Diseases  , e19-e20DOI: ( /j.ajkd )
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

4. Figure 3
IgG4-related TIN with immunoperoxidase staining that shows abundant interstitial IgG4-positive plasma cells (anti-IgG4 immunoperoxidase stain).
American Journal of Kidney Diseases  , e19-e20DOI: ( /j.ajkd )
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

5. Figure 4
IgG4-related TIN with focal granular tubular basement membrane deposits staining with IgG, a finding present in >80% of cases. On the right side, there is focal granular Bowman’s capsule deposits staining with IgG (immunofluorescence anti-IgG).
American Journal of Kidney Diseases  , e19-e20DOI: ( /j.ajkd )
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

6. Figure 5
IgG4-related TIN with immune-type deposits (arrow) along the tubular basement membrane (electron microscopy).
American Journal of Kidney Diseases  , e19-e20DOI: ( /j.ajkd )
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions