1. Date of download: 7/11/2016 From: Upper Airway Sleep-Disordered Breathing in Women Ann Intern Med. 1995;122(7):493-501. doi:10.7326/0003-4819-122-7-199504010-00003 Polygraph showing a progressive increase in respiratory effort over time in a woman with symptoms of sleep-disordered breathing.eses1321322esThis 36-year-old woman had symptoms of daytime fatigue and sleepiness in quiet situations. Note that the end-inspiratory pressure peak became progressively more negative; this peak was monitored with the esophageal catheter (P ) on the second channel from the bottom. When the respiratory effort became too great (as indicated by P monitoring), an arousal occurred. It took 15 minutes for the arousal to occur without any monitored oxygen saturation change. Air flow = nose and mouth thermistors; chest = Respitrace (Ambulatory Monitoring, Inc., Ardsley, New York) recorespiratory disturbance indexing (that is, thorax and abdomen); A, C, and O are electrode placement sites (A = left auricular, C = left central, and O = right occipital); EEG = electroencephalogram; EKG = electrocardiogram indexogram (modified V lead); EMG (channel 3 from top) = chin electromyogram and (channel 7 from top) leg electromyogram; EOG = electro-oculogram; Mic = microphone (note the absence of snoring); and P ( ) = esophageal pressure. The last channel measures oxygen saturation obtained from finger pulse oximetric recorespiratory disturbance indexing. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

2. Date of download: 7/11/2016 From: Upper Airway Sleep-Disordered Breathing in Women Ann Intern Med. 1995;122(7):493-501. doi:10.7326/0003-4819-122-7-199504010-00003 Duration of symptoms in men and women as a function of body mass index (top) and age (bottom).Bars indicate standard deviation. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

3. Date of download: 7/11/2016 From: Upper Airway Sleep-Disordered Breathing in Women Ann Intern Med. 1995;122(7):493-501. doi:10.7326/0003-4819-122-7-199504010-00003 Anatomic abnormalities in a woman with symptoms of sleep-disordered breathing.lefttop rightbottom rightThis woman had a respiratory disturbance index of less than 5 and daytime tiredness. Note her slim neck ( ), overjet ( ), and high ogival hard palate ( ). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

4. Date of download: 7/11/2016 From: Upper Airway Sleep-Disordered Breathing in Women Ann Intern Med. 1995;122(7):493-501. doi:10.7326/0003-4819-122-7-199504010-00003 Percentage of women with sleep-disordered breathing by respiratory disturbance index.Note that 12% of the participants had a respiratory disturbance index of less than 5. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians