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The retina Anatomy:
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Blood supply: - The outer one third (1/3) of retina (including RPE, photoreceptors and half of the outer nuclear layer) - The inner 2/3 of retina
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Blood-Retinal Barrier (BRB):
1- Outer BRB: 2-Inner BRB:
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Applied anatomy: 1- The macula: 2- The fovea: 3- The foveola: 4- Umbo
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Macula 1.5 mm 1 disc Ø 3 mm
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Fovea FAZ μm 7° 4 mm
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Applied anatomy: 1- The macula: 2- The fovea: 3- The foveola:
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Retinal Detachment (RD)
Types of retinal detachment: 1- Rhegmatogenous RD: (Rhegma = break) 2- Non-rhegmatogenous RD: a- Tractional RD: b- Exudative (serous) RD:
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1- Rhegmatogenous RD Causes: a- Idiopathic. b- Myopia. c- Trauma.
d- Intraocular surgery, e.g. cataract surgery. e- Hereditary diseases of vitreous and retina, e.g. Stickler's syndrome. f- In association with Tractional RD.
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1- Rhegmatogenous RD Symptoms: a- Photopsia (flashes of light): PVD
b- Floaters: c- Peripheral visual field defect: d- Decreased central visual acuity (drop vision):
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1- Rhegmatogenous RD
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1- Rhegmatogenous RD
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1- Rhegmatogenous RD
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1- Rhegmatogenous RD
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1- Rhegmatogenous RD
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1- Rhegmatogenous RD
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1- Rhegmatogenous RD
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2- Non-rhegmatogenous RD: a- Tractional RD:
Causes: i- Proliferative diabetic neuropathy. ii- Retinopathy of prematurity "ROP" (retrolental fibropathy or fibroplasias): iii- Sickle cell retinopathy. iv- Penetrating trauma.
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2- Non-rhegmatogenous RD: a- Tractional RD:
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2- Non-rhegmatogenous RD: a- Tractional RD:
Symptoms of tractional RD: i- Visual field defect: ii- Decreased central visual acuity:
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2- Non-rhegmatogenous RD: a- Tractional RD:
Treatment: Vitrectomy
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2- Non-rhegmatogenous RD: b- Exudative RD:
Causes: i- Choroidal tumours. ii- Retinblastoma. iii- Uveitis (posterior uveitis). iv- Posterior scleritis. v- Malignant hypertension. vi- Eclampsia.
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2- Non-rhegmatogenous RD: b- Exudative RD:
Symptoms: Photopsiae are absent. Why?? Floaters. Visual field defect develops suddenly & progress rapidly. Bilateral eye involvement is possible. Treatment???
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Diabetic Retinopathy Pathogenesis: Or microvascular leakage.
either microvascular occlusion. Or microvascular leakage.
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Vascular endothelial groth factor (VEGF)v
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Diabetic Retinopathy The consequences of leakage and increased vascular permeability include the development of intraretinal haemorrahges and oedema.
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Diabetic Retinopathy Clinically DR may be: 1- Background DR.
2- Pre-proliferative DR 3- Proliferative DR. 4- maculopathy, which associates (1), (2) or (3). 5- Advanced diabetic eye disease.
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Diabetic Retinopathy
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Diabetic Retinopathy
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Age-Related Macular Degeneration (AMD)
A common, chronic, progressive degenerative disorder of the macula that affect peoples above 50. dry AMD wet AMD
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Macula 1.5 mm 1 disc Ø 3 mm
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AMD dry
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