EARIP- European Asthma Research and Innovation Partnership Dr Samantha Walker (Asthma UK) “Does innovative research for allergy and respiratory disease in the European Union benefit patients?” - 17 th June 2014

Why asthma? 30 million people with asthma in Europe By 2020 approximately 120,000 people in Europe will die of an asthma attack and over 4 million hospitalisations will be needed by those most severely affected Treatment costs about €20bn annually and lost productivity costs €9.8bn per year There are no effective treatments for about 5% of people with asthma, and we have had few new breakthrough drug treatments The treatments are not always appropriate (because the phenotypes of asthma are not well characterised, and because existing drugs/treatment regimens may be inappropriate for many, amongst several reasons)

Co-ordinated by Asthma UK 12 partners from across Europe €500,000 grant, funded under the FP7 programme Supported by 50+ consortium members The EARIP project

EARIP - Aims To define the activities and investment needed to: Reduce asthma deaths in Europe by 25% within 10 years and 50% within 20 years Reduce hospitalisations by 50% Increase optimum self-management (through uptake of self-management plans) by 20% To increase funding for asthma research across Europe

Structural The approach to address the asthma ‘problem’ in Europe Biological EARIP EARIP Work Packages (WP ) Clinical & translational

WP1 co-ordination & dissemination WP2 - Identify better ways to develop new biological targets and use existing ones more effectively WP3 - Understand asthma phenotypes with a view to developing better treatments WP4 – Criteria to develop better and more efficient healthcare systems across Europe for people with asthma WP5 - Define and agree plans to improve diagnostic and patient self-management tools WP6 - Agree pan-European asthma research priorities to create an asthma roadmap so that researchers know what to focus on WP7 - Establish what is needed to create a European Innovation Partnership (EIP) for the management of asthma WP8 - Create a proposal to establish a European network of clinical asthma research facilities

Patient representatives Patient representatives in each WP Training and support provided by Asthma UK and EFA Attend workshops to provide input and review the reports and outputs of the WP’s Meet annually to discuss the overall direction of the project More widely patients will be asked to complete surveys associated with work package activities

Project progress M10 of the project & progress across all WP’s: -WP2&3 workshop at the EAACI congress -WP4 completed review -WP5 working groups formed -WP6 survey – June WP7 influencing and stakeholder mapping - WP8 survey – July 2014

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