1 |1 | Countries using and planning to introduce IPV and the global status of bOPV registration Countries using and planning to introduce IPV and the global status of bOPV registration

2 |2 | Countries using and planning to introduce IPV February 2016 status report This slide deck provides a summary per country on the status of planning for the introduction of Inactivated Poliomyelitis Vaccine (IPV). It also includes a summary of the global status of national registration of bivalent Oral Polio Vaccine (bOPV), in preparation for the switch from trivalent OPV (tOPV) to bOPV. Information here is updated monthly based on information shared by WHO and UNICEF Regional Offices. Please contact with any questions or updates on this Definitions Formal decision to introduce: The country has documentation of its decision to introduce IPV which has been verified by the relevant WHO Regional Office, or for Gavi eligible countries, a complete application for IPV has been submitted to the Gavi Secretariat. Tracking these decisions and informal intents provide an indication of the global trend towards meeting the targets of the Polio Eradication and Endgame Strategic Plan.

3 |3 | Countries using IPV vaccine to date and formal decision to introduce Data source: WHO/IVB Database, as of 02 February 2016 Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Date of slide: 2 February 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Introduced to date* (158 countries or 81%) Formal commitment to introduce in 2016 (36 countries or 19%) Not available Not applicable Since January 2013, the following countries have introduced IPV: Kazakhstan, Peru & Singapore (July 2013); Micronesia (August 2013); Libya (April 2014); Albania & Panama (May 2014); Nepal & Tunisia (September 2014); Philippines (October 2014); China (December 2014); Comoros, Senegal & Serbia (January 2015); Colombia & Nigeria (February 2015); Bangladesh & Maldives (March 2015); DR Congo, DPR Korea & The Gambia (April 2015); Madagascar (May 2015); Cote d'Ivoire, Grenada, Kiribati, Morocco, St Vincent and the Grenadines & Sudan (June 2015); Bhutan, Cameroon, Niger, Pakistan, Philippines & Sri Lanka (July 2015); Benin, Chad, Papua New Guinea, The Former Yug. Rep. of Macedonia (August 2015); Afghanistan, CAR, Dominica, Guyana, Iran, Jamaica, Seychelles & Solomon Islands (September 2015); Bahamas, Lao People's Dem Rep, Nauru, Samoa (October 2015); Antigua and Barbuda, Botswana, Burundi, Cook Islands, Guinea, India, Mauritania, Mauritius, Mozambique, Namibia, Nicaragua, St Lucia, Suriname, Tuvalu, Vanuatu & Yemen (November 2015); Algeria, Belize, Cambodia, Dominical Rep, Ecuador, Ethiopia, Fiji, Gabon, Georgia, Honduras, Kenya, Myanmar, Paraguay, St Kitts & Nevis, S. Sudan, Thailand, Tonga & Trinidad & Tobago (December 2015); Cuba, El Salvador, Guatemala, Haiti, Iraq & Venezuela (Bolivian Rep of) (January 2016); Timor-Leste (1 February 2016) * Including partial introduction in Haiti, India & Venezuela

4 |4 | IPV introduction status and planned introduction in 2016 Date of slide: 2 February 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Introduced to date* (158 countries or 81%) Introduction planned in March 2016 Introduction planned after April 2016 Not available (21 countries or 11%) Not applicable Introduction planned in April 2016 Introduction planned in February 2016 * Including partial introduction in Haiti, India & Venezuela (9 countries or 5%) (3 countries or 1.5%) Since January 2013, the following countries have introduced IPV: Kazakhstan, Peru & Singapore (July 2013); Micronesia (August 2013); Libya (April 2014); Albania & Panama (May 2014); Nepal & Tunisia (September 2014); Philippines (October 2014); China (December 2014); Comoros, Senegal & Serbia (January 2015); Colombia & Nigeria (February 2015); Bangladesh & Maldives (March 2015); DR Congo, DPR Korea & The Gambia (April 2015); Madagascar (May 2015); Cote d'Ivoire, Grenada, Kiribati, Morocco, St Vincent and the Grenadines & Sudan (June 2015); Bhutan, Cameroon, Niger, Pakistan, Philippines & Sri Lanka (July 2015); Benin, Chad, Papua New Guinea, The Former Yug. Rep. of Macedonia (August 2015); Afghanistan, CAR, Dominica, Guyana, Iran, Jamaica, Seychelles & Solomon Islands (September 2015); Bahamas, Lao People's Dem Rep, Nauru, Samoa (October 2015); Antigua and Barbuda, Botswana, Burundi, Cook Islands, Guinea, India, Mauritania, Mauritius, Mozambique, Namibia, Nicaragua, St Lucia, Suriname, Tuvalu, Vanuatu & Yemen (November 2015); Algeria, Belize, Cambodia, Dominical Rep, Ecuador, Ethiopia, Fiji, Gabon, Georgia, Honduras, Kenya, Myanmar, Paraguay, St Kitts & Nevis, S. Sudan, Thailand, Tonga & Trinidad & Tobago (December 2015); Cuba, El Salvador, Guatemala, Haiti, Iraq & Venezuela (Bolivian Rep of) (January 2016); Timor-Leste (1 February 2016) Data source: WHO/IVB Database, as of 02 February 2016 Map production Immunization Vaccines and Biologicals (IVB), World Health Organization

5 |5 | Countries using IPV vaccine to date and introductions planned according to Gavi eligibility status Date of slide: 2 February 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Introduced to date(158 countries or 81%) Gavi countries with formal commitment to introduce in 2016 (29 countries or 15%) Non Gavi countries with formal commitment to introduce in 2016 (7 countries or 4%) Not available Not applicable Since January 2013, the following countries have introduced IPV: Kazakhstan, Peru & Singapore (July 2013); Micronesia (August 2013); Libya (April 2014); Albania & Panama (May 2014); Nepal & Tunisia (September 2014); Philippines (October 2014); China (December 2014); Comoros, Senegal & Serbia (January 2015); Colombia & Nigeria (February 2015); Bangladesh & Maldives (March 2015); DR Congo, DPR Korea & The Gambia (April 2015); Madagascar (May 2015); Cote d'Ivoire, Grenada, Kiribati, Morocco, St Vincent and the Grenadines & Sudan (June 2015); Bhutan, Cameroon, Niger, Pakistan, Philippines & Sri Lanka (July 2015); Benin, Chad, Papua New Guinea, The Former Yug. Rep. of Macedonia (August 2015); Afghanistan, CAR, Dominica, Guyana, Iran, Jamaica, Seychelles & Solomon Islands (September 2015); Bahamas, Lao People's Dem Rep, Nauru, Samoa (October 2015); Antigua and Barbuda, Botswana, Burundi, Cook Islands, Guinea, India, Mauritania, Mauritius, Mozambique, Namibia, Nicaragua, St Lucia, Suriname, Tuvalu, Vanuatu & Yemen (November 2015); Algeria, Belize, Cambodia, Dominical Rep, Ecuador, Ethiopia, Fiji, Gabon, Georgia, Honduras, Kenya, Myanmar, Paraguay, St Kitts & Nevis, S. Sudan, Thailand, Tonga & Trinidad & Tobago (December 2015); Cuba, El Salvador, Guatemala, Haiti, Iraq & Venezuela (Bolivian Rep of) (January 2016); Timor-Leste (1 February 2016) * Including partial introduction in Haiti, India & Venezuela Data source: WHO/IVB Database, as of 02 February 2016 Map production Immunization Vaccines and Biologicals (IVB), World Health Organization

6 |6 | 36 countries introducing IPV between 2 February and September 2016 Tier 1 countries are countries with cVDPV2 transmission or cVDPV2 reported since 2000 & WPV endemic countries Tier 2 countries are countries with cVDPV 1/3 since 2000 or large /medium size countries with DTP3 coverage <80% in the past 3 years as per WUENIC Feb-16Mar-16Apr-16After April-16 AzerbaijanChileArgentinaAngola BoliviaMaliCabo VerdeArmenia CongoUgandaDjiboutiBurkina Faso EgyptEritrea Equatorial GuineaGhana Guinea-BissauIndonesia LesothoKyrgyzstan Sao Tome & PrincipeLiberia SwazilandMalawi Mongolia Rep. of Moldova Rwanda Sierra Leone Tajikistan Togo Turkmenistan United Rep. of Tanzania Uzbekistan Viet Nam Zambia Zimbabwe Legend Tier 2 countries Data source: WHO/IVB Database, as of 02 February 2016 Map production Immunization Vaccines and Biologicals (IVB), World Health Organization

7 |7 | Tier 1 and 2 Countries using IPV vaccine to date and formal decision to introduce Tier 1 countries are countries with cVDPV2 transmission or cVDPV2 reported since 2000 & WPV endemic countries Tier 2 countries are countries with cVDPV 1/3 since 2000 or large /Medium size countries with DTP3 coverage <80% in the past 3 years as per WUENIC Data source: WHO/IVB Database, as of 02 February 2016, based on 36 tier 1 & 2 countries Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Date of slide: 2 February 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Introduced to date* (30 countries or 83%) (6 countries or 17%) Formal commitment to introduce in 2016 (158 countries) Not applicable / not available / not Tier 1 or 2 countries * Including partial introduction in Haiti and India Since January 2013, the following Tier 1 and 2 countries have introduced IPV: The Philippines (October 2014), China (December 2014), Nigeria (February 2015), DR Congo (April 2015), Madagascar (May 2015), Cameroon, Niger and Pakistan (July 2015); Benin, Chad and Papua New Guinea (August 2015); Afghanistan and CAR (September 2015); Lao People's Democratic Republic (October 2015); Guinea, India, Mauritania, Mozambique, Somalia & Yemen (November 2015); Cambodia, Dominican Rep., Ethiopia, Gabon, Kenya, Myanmar & S. Sudan (December 2015); Haiti & Iraq (January 2016); Timor-Leste (1 February 2016)

8 |8 | Middle Income Countries using IPV vaccine to date and formal decision to introduce Data source: WHO/IVB Database, as of 02 February 2016 based on 100 middle income countries (MIC) as per last World Bank classification Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Date of slide: 2 February 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Introduced to date (80 countries or 80%) Formal commitment to introduce in 2016 (20 countries or 20%) Not available / Not applicable / Non MIC Since January 2013, the following MIC have introduced IPV: Kazakhstan (July 2013); Peru (July 2013); Libya (March 2014); Albania (May 2014); Panama (July 2014); Tunisia (September 2014); Philippines (October 2014); China (December 2014); Senegal (January 2015); Serbia (January 2015); Colombia (February 2015); Maldives (March 2015) and Cote d'Ivoire, Kiribati, Morocco, St Vincent and the Grenadines & Sudan (June 2015); Bhutan, Cameroon, Pakistan & Sri Lanka (July 2015); Papua New Guinea & the former Yugoslav Rep. of Macedonia (August 2015); Dominica, Guyana, Iran, Jamaica & Solomon Islands (September 2015); Lao People's Democratic Rep & Samoa (October 2015); Botswana, India, Mauritania, Mauritius, Namibia, Nicaragua, St Lucia, Tuvalu, Vanuatu & Yemen (November 2015); Algeria, Belize, Dominican Rep, Ecuador, Fiji, Gabon, Georgia, Honduras, Kenya, Myanmar, Paraguay, Thailand & Tonga (December 2015); Cuba, El Salvador, Iraq & Guatemala (January 2016); Timor- Leste (1 February 2016)

9 |9 | Overview of Global birth cohort by IPV status/tier (100% = 136.1million births in 2015) Data source: WHO/IVB Database, as of 02 February 2016 and United Nations, Department of Economic and Social Affairs, Population Division (2015). World Population Prospects: The 2015 Revision

10 | bOPV registration status for routine immunization Data source: WHO/IVB Database, as of 02 February 2016 based on 148 OPV user countries and 7 Territories Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Date of slide: 2 February 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Approval for use(128 countries) Review in progress(11 countries ) Pending submission (5 countries) Not available/ non switch countries Not applicable (switch area territories) (46 countries) + 4 countries switching from tOPV to IPV