Cloning Catalyst: What is a somatic cell? What is a gamete? What is a stem cell? Give one example of how stem cells could be used in medicine to help people. Write in complete sentences! Don’t talk during the Catalyst!

By the end of today, all SWBAT… Objectives By the end of today, all SWBAT… Describe the steps necessary to clone organisms Evaluate pros and cons of cloning organisms

Agenda Catalyst Cloning Cloning Video Cloning Debate Exit Question

Cloning Key Point #1: Cloning is the process of creating a genetically identical copy of an organism by a somatic cell nuclear transfer.

Don’t copy, just look.

Sure, Mr. LY. What does this look like in real life though? I'M GLAD YOU ASKED!!!!

Steps of a Somatic Cell Transfer The nucleus is removed from an egg The nucleus is removed from the cell that needs to be cloned The nucleus from the cell that needs to be cloned is put into the empty egg. It is given a jolt of electricity, causing it to divide and grow.

Species that have been successfully cloned to date Tadpole: 1952 Carp: 1963 Sheep: 1996 – FIRST ADULT ANIMAL TO BE CLONED. Cat: 2002 Mule: 2003 Horse: 2005 Camel: 2005 Rhesus Monkey: 2007 Human: ????

Why clone animals? Save endangered species Key Point #2: There are many reasons to clone animals. Save endangered species San Diego Zoo Audubon Zoo Bring extinct species back to life Nutritious and delicious food

Implications of cloning In 2007, scientists cloned a rhesus monkey embryo and harvested monkey stem cells. 2 minutes, Pair-Share How would society change if we could clone humans?

Cloning Key Point #3: We can clone human embryos to harvest embryonic stem cells for research Dissect the embryo to remove stem cells No worries about the immune system rejecting the stem cells This is what most people think of when I mention “human cloning.” This is not what we’re talking about.

Stem Cell Video You should be able to answer the questions on the worksheet. Head up, pay attention. Keep these questions in mind: What are we trying to do with cloned human cells? What are the potential benefits? What are the ethical issues? WHOA! A LOT TO THINK ABOUT. Open in internet explorer.

Prompt #1 It is morally acceptable to clone animals (for any of the reasons we have discussed today)

Prompt #3 Since a blastocyst is as big as the tip of a pin, it should not be considered to be a human life.

Prompt #2 People should be able to destroy embryos to improve the life of already living humans.

Cloning humans is unnatural and should not be pursued. Prompt #4 Cloning humans is unnatural and should not be pursued.

Prompt #5 Overall, the benefits of cloning (humans and animals) outweigh the negative consequences.

Independent work time on the worksheet

Key Point Wrap-Up Key Point #1: Cloning is the process of creating a genetically identical copy of an organism by a somatic cell nuclear transfer. Key Point #2: There are many reasons to clone animals. Key Point #3: We can clone human embryos to harvest stem cells for research.

Describe the four steps necessary to clone an organism. Exit Questions Describe the four steps necessary to clone an organism. Write in complete sentences! Don’t talk during the Exit Question!