Parkinson’s Disease (PD) -progressive neurodegenerative disease affecting motor ability -third most common neurologic disorder of older adults
Population at risk: Male> Female Two types 1) yrs. of age (young onset) Michael J. Fox at age 30 2) yrs. of age (idiopathic) over 1 million affected in US with 50, ,000 new cases each year
Genetics- only about 5% Environmental factors -rural living -well water -pesticides/herbicides Age
Presence of motor dysfunction with 4 cardinal symptoms resting tremor akinesia (slowness of body movement) rigidity Postural instability NO PREVENTION, NO CURE
Degeneration of dopamine-producing neurons in the substantia nigra of the midbrain › Disrupts the balance of: dopamine (DA) – neurotransmitter for normal functioning of the extrapyramidal motor system Acetylcholine (Ach) Symptoms do not occur until 80% of the neurons in the substantia nigra are lost
Fatigue Problems with manual dexterity Slight tremor Rigidity Changes in facial expression Uncontrolled drooling
Dementia Dysphagia Excessive perspiration Orthostatic hypotension No specific diagnostic tests