CENTER FOR PROCESS ANALYTICAL CHEMISTRY UNIVERSITY OF WASHINGTON, SEATTLE

 Provides a Forum for Multidisciplinary Participation in Process Analytical Technology Definition, Creation, and Utilization  Established in 1984, the Objective of the Center is to Address Challenges in Real-Time and Continuous Process Monitoring and Control CPAC is a Consortium of Industrial Sponsors, National Laboratories and Government Agencies

CPAC Activities Semiannual Sponsor Meetings Graduate Education Summer Institute Industry Segment Meetings Technical Workshops Visiting Scientist Program Pittcon, IFPAC,  TAS

Core Research Areas  Chemometrics  Sensors  Spectroscopy / Imaging  Chromatography  MicroFlow Analysis  Process Control

Multidisciplinary  Chemistry  Chemical Engineering  Electrical Engineering  Bioengineering  Applied Physics  Forestry  Mechanical Engineering  Food Science & Engineering  Health Sciences

PEER COMMUNICATION  BENCHMARKING  CLEARING HOUSE  FOCUS GROUPS

CPAC Industrial Sponsors Air Products Amgen Amersham Bioscience Ashland Aventis Baxter Healthcare Boeing Bristol-Myers Squibb Cargill CPC Systems Chevron Texaco Dow Chemical Dupont ExxonMobil Chemical Genentech Goodyear Tire & Rubber Honeywell Inc. ICI Kaiser Optical Systems Kimberly-Clark Kraft Foods Master Foods Merck & Co. Metso Automation Parker Hannifin Pharmacia Phillips Petroleum Rohm & Haas Rosemount Analytical Swagelok Systematix Controls ThermoONIX 3M

CPAC Government Sponsors National Institute of Standards & Technology Pacific Northwest National Westinghouse Savannah River Co.

Sponsor Focus Groups  Oil & Petrochemicals  Chemicals & Materials  Food & Consumer Products  Bio Tech / Pharmaceuticals  National Labs & Agencies  Instrument Companies

REVOLUTIONARY ADVANCES THAT ARE AFFECTING MEASUREMENT SCIENCE MEASUREMENT INFORMATION PROCESSING MINIATURIZATION ENGINEERED MATERIALS ELECTRO-OPTICS

Advances in Microtechnology. Electronics computers, communications MEMS microfluidics, microoptics, bulk micromachining Nanotechnology new materials and interface control

CPAC STRATEGIC RESEARCH AREAS  SURFACE AND INTERFACIAL CHARACTERIZATION AND CONTROL  MULTICOMPONENT MATERIALS CHARACTERIZATION AND CONTROL  VERSATILE MICROANALYTICAL SYSTEMS  PROCESS MONITORING, MODELING AND CONTROL PROBLEMS SYSTEMS

1996 Summer Institute with special emphasis on: VERSATILE MICRO- ANALYTICAL SYSTEMS and PROCESS MONITORING, MODELING AND CONTROL JULY 17-19, 1996 TOPICS IN PROCESS ANALYSIS AND CONTROL

CPAC INITIATIVES OPEN -NEW SAMPLING AND SENSOR INITIATIVE (NeSSI) -CONNECTIVITY INTIATIVE (ConnI) -CHEMOMETRICS ON-LINE INITIATIVE (COPA) CLOSED -MICRO-INSTRUMENTATION FOR HIGH THROUGHPUT EXPERIMENTATION PLATFORM -FERMENTATION MONITORING AND CONTROL PLATFORM (FermI)

2002 Summer Institute IMPROVING HIGH THROUGHPUT EXPERIMENTATION via MICRO-ANALYTICAL SYSTEMS and PROCESS MONITORING, MODELING AND CONTROL JULY 17-19, 2002

Prospects for Improving Process Optimization using Miniaturization Technology MICRO-INSTRUMENTATION AND MICRO-REACTORS

THE DRIVER IS THE NEED FOR HIGH THROUGHPUT EXPERIMENTAION DISCOVERY SCREENING PROCESS DEVELOPMENT PROCESS CONTROL

MICROREACTORS BATCH CONTINOUS

SOME RELEVANT CURRENT CPAC RESEARCH EFFORTS MICRO-LC SURFACE TENSION DETECTION GCxGC FRINGE FIELD SENSORS VAPOCHROMIC SENSORS RAMAN GRATED LIGHT REFLECTIVE SPECTROSCOPY REFLECTOMETRY FLOW-THROUGH PARTICLE ANALYZER SURFACE PLASMON RESONANCE MINI-MASS SPECTROMETER DATA HANDLING

NeSSI has become an Enabling technology for... –Miniature physical sensors –Miniature chemical composition sensors Courtesy of Panametrics & Swagelok Courtesy of Rosemount Analytical Courtesy of Applied Analytics Porter Instruments and the Swagelok Co.

Micro-reactor / NeSSI connection being planned at CPAC

NeSSI with Analytical will Impact Process Optimization Process Control Analytical Method Development Product Development