Blood Our body’s most important substance

Intro to Blood: The Video Clip

Blood: The Parts PlasmaPlasma Red Blood CellsRed Blood Cells White Blood CellsWhite Blood Cells PlateletsPlatelets

Blood: The Plasma Makes up 55% of bloodMakes up 55% of blood Mostly waterMostly water Yellowish in colorYellowish in color Plasma proteins:Plasma proteins: Regulate blood volumeRegulate blood volume Transport substancesTransport substances Help with clottingHelp with clotting

Plasma: The Video Clip

Blood: Red blood cells Most numerous blood cellsMost numerous blood cells Job is to CARRY OXYGENJob is to CARRY OXYGEN RED = HOLDING OXYGENRED = HOLDING OXYGEN BLUE = GAVE OXYGEN TO CELLSBLUE = GAVE OXYGEN TO CELLS Hemoglobin: Very special proteinHemoglobin: Very special protein Contains IRON (HEME!)Contains IRON (HEME!) Binds oxygen in lungsBinds oxygen in lungs Neat fact: RBC’s do not have a nucleus!Neat fact: RBC’s do not have a nucleus!

RBC’s: The Video Clip

Blood: White Blood Cells Much less abundant but LARGEMuch less abundant but LARGE Different typesDifferent types Ex. PhagocytesEx. Phagocytes Who remembers phagocytosis!?Who remembers phagocytosis!? Job:Job: Work with immune system to attack foreign bodiesWork with immune system to attack foreign bodies

WBC’S: The Video Clip

Blood: Platelets Work with plasma proteins to help CLOT BLOODWork with plasma proteins to help CLOT BLOOD Become “sticky” when blood vessel is brokenBecome “sticky” when blood vessel is broken

Platelets: The Video Clip

Blood Types Each contains different proteins which make donating and receiving blood complicated! These proteins are:Each contains different proteins which make donating and receiving blood complicated! These proteins are: Antigen = anything that triggers an immune response IF recognized as being “foreign”.Antigen = anything that triggers an immune response IF recognized as being “foreign”. Antibody = the proteins that recognize (match) specific antigens.Antibody = the proteins that recognize (match) specific antigens. 4 blood types:4 blood types: Type A: contains “A” antigens and “B” antibodiesType A: contains “A” antigens and “B” antibodies Type B: contains “B” antigens and “A” antibodiesType B: contains “B” antigens and “A” antibodies Type AB: contains both “A” and “B” antigens and NO antibodiesType AB: contains both “A” and “B” antigens and NO antibodies Type O: contains NO antigens but BOTH “A” and “B” antibodies.Type O: contains NO antigens but BOTH “A” and “B” antibodies.

How Do Blood Transfusions Work? The transfusion will work if a person who is going to receive blood has a blood group that doesn't have any antibodies against the donor blood's antigens.The transfusion will work if a person who is going to receive blood has a blood group that doesn't have any antibodies against the donor blood's antigens. But if a person who is going to receive blood has antibodies matching the donor blood's antigens, the red blood cells in the donated blood will clump or agglutinate.But if a person who is going to receive blood has antibodies matching the donor blood's antigens, the red blood cells in the donated blood will clump or agglutinate.

Blood Types: Donating and Receiving Type A:Type A: Donates to: A AND ABDonates to: A AND AB Receives from: A or OReceives from: A or O Type B:Type B: Donates to: B AND ABDonates to: B AND AB Receives from: B or OReceives from: B or O Type AB:Type AB: Donates to: AB onlyDonates to: AB only Receives from: A, B, AB, or OReceives from: A, B, AB, or O UNIVERSAL RECIPIENT!UNIVERSAL RECIPIENT! Type O:Type O: Donates to: A, B, AB, or ODonates to: A, B, AB, or O UNIVERSAL DONOR!UNIVERSAL DONOR! Receives from: O onlyReceives from: O only

Blood Types: The Video Clip