1 Yellow Fever Allison Gregg

2 General History thousands of years old originated in Africa brought to the U.S. in the 1500s

3 General History Walter Reed discovered how YF is transmitted-mosquitoes Yellow Fever from yellow color from liver failure

4 General History and Structure Asian countries are habitats for mosquitoes that carry Yellow fever Single stranded RNA Shape: spheroidal

5 How YF is Transmitted 2 transmission methods: –“jungle cycle” –“urban cycle”

6 How YF is Transmitted can only be transmitted through mosquito bites cannot survive outside its vector-the mosquito

7 How YF is Transmitted originally from monkeys becomes permanently fixed in salivary glands of mosquito

8 Who is affected

9 tropical regions of Africa and South America 30,000 deaths each year worldwide estimate of 200,000 cases a year

10 Who is affected epidemics usually affect 20% of the population unvaccinated populations can have death rates above 50%

11 Symptoms incubation period of 3-6 days “acute” phase “toxic” phase

12 Symptoms 15% go into “toxic phase” 50% of “toxic” cause death hard to diagnose disease

13 Vaccine a live-virus vaccine Vaccine must be given every 10 years 95% immunity a week after vaccination

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