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Viral Diseases of the Digestive and Lymphoid Organs

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Presentation on theme: "Viral Diseases of the Digestive and Lymphoid Organs"— Presentation transcript:

1 Viral Diseases of the Digestive and Lymphoid Organs
Plate 84 Viral Diseases of the Digestive and Lymphoid Organs



4 Viral Gastroenteritis
Viral gastroenteritis: inflammation of stomach and intestines Often called “stomach flu”, although it is not caused by the influenza virus Symptoms: primarily diarrhea and vomiting, but also headaches, fever, and stomach-ache

5 Yellow fever Sometimes known as “yellow jack” or “black vomit”
Called “yellow fever” because of the jaundice that it causes RNA icosahedral (Flaviviridae family) virus

6 Symptoms 3-6 days of incubation, then 3-4 days of fever and muscle pain Most patients improve and symptoms disappear 15% of patients enter a 2nd toxic phase: Bleeding from mouth, nose, eyes, and/or stomach Kidney failure Jaundice 50% mortality in 14 days No cure, just treatment for symptoms

7 Symptoms Jaundice – “yellowing” of skin and eyes
Bile passes from the gallbladder and/or liver into the bloodstream

8 Transmission The virus is transmitted via mosquito bites
Virus passes from the mosquito’s saliva to the human bloodstream Can also pass from monkeys to mosquitoes to humans Aedes aegypti mosquito

9 Transmission Estimated 200,000 cases and 30,000 deaths per year worldwide Vaccine is very effective Cases have increased over the past 20 years due to urbanization, deforestation, and climate change

10 Philadelphia Summer 1793, French refugees (some who had Yellow Fever) fled the Haitian Revolution and came to Philadelphia By November 1793, about 5,000 Philadelphians had died (more than 10% of population) Summer 1794, Yellow Fever returned, but not as severely, and also in 1796 and 1797 Another severe epidemic came in 1798, killing 1,292 Philadelphians At the peak of the 1798 epidemic, all but 7,000 residents had left the city

11 Dengue Fever Also known as “break-bone” fever
RNA icosahedral (Flaviviridae family) virus

12 DF - Symptoms Dengue fever has symptoms which can be very similar initially to flu Most people suffer from headaches and fever, some get muscle and bone pains An infected person can feel tired for up to three months, but will not usually need treatment May lead to Dengue Hemorrhagic Fever (DHF), which is potentially lethal

13 DF - Symptoms (continued)
Itchy rash. Everywhere I had ever been injured hurt again. Achy like the flu but worse. Exhausted. Literally took months to regain full energy and stamina.

14 DF - History Dengue fever originated in primates and “jumped” to humans years ago Because of disruption from WWII and international trading of cargo, the Aedes mosquito has spread to tropical regions around the world Not until 1981 that the disease became problematic in Latin America and the Caribbean

15 DF - Location 40% of the world’s population live in areas where they are at risk for dengue transmission WHO estimates that there are million infections a year and 22,000 deaths

16 DF - Treatment There is no cure for dengue fever nor is there specific medication for it Patients should rest, take pain-relievers, and drink plenty of fluids

17 DF - Transmission Dengue viruses are mainly transmitted by the bite of infected Aedes aegypti mosquitoes

18 Mononucleosis The “kissing disease”
Epstein-Barr virus (human herpesvirus 4)

19 Mono - Symptoms

20 Mono - Symptoms


22 Mono Symptoms - Swollen Tonsils

23 Mono - Transmission Virus spread through salivary drops

24 Hepatitis A RNA enterovirus (hepatitis A virus – HAV)

25 HAV - Symptoms Can cause: Swelling of the liver Jaundice Fatigue
Loss of appetite Diarrhea

26 HAV - Transmission Spread primarily by food or water contaminated by stool from an infected person Eating food prepared by someone with HAV who did not wash their hands after using the bathroom

27 Hepatitis B Hepadnavirus (hepatitis B virus – HBV)

28 HBV - Symptoms Short-term HBV resembles symptoms of the flu
Possible symptoms include fever, dark urine, vomiting, and jaundice Long-term HBV (chronic HBV) lasts a lifetime and can lead to scarring of the liver, liver failure, and liver cancer Interferon can be used to slow the virus from damaging the liver

29 HBV - Transmission HBV is spread through contact with blood, semen, or other body fluids of an infected person

30 Hepatitis C Symptoms Long term Info.
jaundice, fatigue, dark urine, nausea Long term infections (55-85%), leading indication for transplant, Info. No vaccine, interferon, do not share personal items, rarely STD

31 Hepatitis D Symptoms Long Term Info.
jaundice, fatigue, tea-colored urine joint pain Long Term more sever acute disease & risk of failure Info. acquires along with HBV

32 Hepatitis E Symptoms Long Term Info.
Jaundice, dark urine, loss appetite, fatigue Long Term no long term often seen in pregnancy Info. highest among yo, contaminated water

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