Guidelines for the diagnosis and treatment of non-ST- segment elevation acute coronary syndromes by Jean-Pierre Bassand, Christian W. Hamm, Diego Ardissino,

Slides:



Advertisements
Similar presentations
Unstable angina and NSTEMI
Advertisements

Long-term compliance with beta-blockers, angiotensin- converting enzyme inhibitors, and statins after acute myocardial infarction by Gunnar H. Gislason,
British Cardiac Intervention Society Risk Assessment In Acute Coronary Syndromes Dr David Newby BHF Senior Lecturer in Cardiology Associate Director of.
Guidelines for the diagnosis and treatment of pulmonary hypertension by, Nazzareno Galiè, Marius M. Hoeper, Marc Humbert, Adam Torbicki, Jean-Luc Vachiery,
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 by, John J.V. McMurray, Stamatis Adamopoulos, Stefan D. Anker, Angelo.
The relationship between body mass index, treatment, and mortality in patients with established coronary artery disease: a report from APPROACH by Antigone.
Amr Hassan Mostafa, MD, FSCAI A. Professor of Cardiology Cairo University Cairo, Egypt Egypt Combat MI, March 24-25, Cairo Sheraton.
An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn.
Acute STEMI: current approach
Guidelines on myocardial revascularization by,, William Wijns, Philippe Kolh, Nicolas Danchin, Carlo Di Mario, Volkmar Falk, Thierry Folliguet, Scot Garg,
Clopidogrel pre-treatment in stable angina: for all patients >6 h before elective coronary angiography or only for angiographically selected patients a.
High spatial resolution myocardial perfusion cardiac magnetic resonance for the detection of coronary artery disease by Sven Plein, Sebastian Kozerke,
Executive summary of the guidelines on the diagnosis and treatment of acute heart failure by Markku S. Nieminen, Michael Böhm, Martin R. Cowie, Helmut.
Guidelines on the diagnosis and management of acute pulmonary embolism by, Adam Torbicki, Arnaud Perrier, Stavros Konstantinides, Giancarlo Agnelli, Nazzareno.
“Challenging practice in non-ST segment elevation Acute Coronary Syndromes (ACS)” Professor Jennifer Adgey Royal Victoria Hospital, Belfast 26th January.
Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009)‏ by,, Gilbert Habib, Bruno Hoen, Pilar Tornos, Franck.
Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment.
Safety and Efficacy of Intravenous Enoxaparin in Elective Percutaneous Coronary Intervention: an International Randomized Evaluation (STEEPLE) Presented.
Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with.
Platelet thrombin receptor antagonism and atherothrombosis by Dominick J. Angiolillo, Davide Capodanno, and Shinya Goto EHJ Volume 31(1):17-28 January.
Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay:
The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle,
Guidelines for cardiac pacing and cardiac resynchronization therapy by Panos E. Vardas, Angelo Auricchio, Jean-Jacques Blanc, Jean-Claude Daubert, Helmut.
Interventions for prevention of post-operative atrial fibrillation and its complications after cardiac surgery: a meta-analysis by David C. Burgess, Michael.
Awareness and perception of heart failure among European cardiologists, internists, geriatricians, and primary care physicians by Willem J. Remme, John.
Bone marrow cells are a rich source of growth factors and cytokines: implications for cell therapy trials after myocardial infarction by Mortimer Korf-Klingebiel,
Genous™ endothelial progenitor cell capturing stent vs. the Taxus Liberté stent in patients with de novo coronary lesions with a high-risk of coronary.
Guidelines on the management of valvular heart disease by Alec Vahanian, Helmut Baumgartner, Jeroen Bax, Eric Butchart, Robert Dion, Gerasimos Filippatos,
Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty:
Acute Coronary Syndromes Risk-Stratification Pathophysiology Diagnosis Initial Therapy Risk-Stratification Risk-Stratification Invasive vs Conservative.
Excessive heart rate increase during mild mental stress in preparation for exercise predicts sudden death in the general population by Xavier Jouven, Peter.
Guidelines for the diagnosis and management of syncope (version 2009)‏ by,,,,,,,,,,,,, Angel Moya, Richard Sutton, Fabrizio Ammirati, Jean-Jacques Blanc,
An update on regional variation in cardiovascular mortality within Europe by Jacqueline Müller-Nordhorn, Sylvia Binting, Stephanie Roll, and Stefan N.
Gregg W. Stone MD for the ACUITY Investigators Gregg W. Stone MD for the ACUITY Investigators A Prospective, Randomized Trial of Bivalirudin in Acute Coronary.
The influence of body mass index on mortality and bleeding among patients with or at high-risk of atherothrombotic disease by Koon-Hou Mak, Deepak L. Bhatt,
European guidelines on cardiovascular disease prevention in clinical practice: executive summary by Ian Graham, Dan Atar, Knut Borch-Johnsen, Gudrun Boysen,
Acute viral myocarditis by Robert Dennert, Harry J. Crijns, and Stephane Heymans EHJ Volume 29(17): August 25, 2008 Published on behalf of the.
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008 by , Kenneth Dickstein, Alain Cohen-Solal, Gerasimos Filippatos,
Longer-term effects of cardiac resynchronization therapy on mortality in heart failure [the CArdiac REsynchronization-Heart Failure (CARE-HF) trial extension.
Short stature is associated with coronary heart disease: a systematic review of the literature and a meta-analysis by Tuula A. Paajanen, Niku K.J. Oksala,
Dronedarone in patients with congestive heart failure: insights from ATHENA by Stefan H. Hohnloser, Harry J.G.M. Crijns, Martin van Eickels, Christophe.
Date of download: 5/27/2016 Copyright © The American College of Cardiology. All rights reserved. From: The thrombolysis in myocardial infarction risk score.
Date of download: 5/28/2016 From: Optimal Timing of Coronary Invasive Strategy in Non–ST-Segment Elevation Acute Coronary Syndromes: A Systematic Review.
Gregg W. Stone MD for the ACUITY Investigators A Prospective, Randomized Trial of Bivalirudin in Acute Coronary Syndromes Final One-Year Results from the.
Prediction of fatal or near-fatal cardiac arrhythmia events in patients with depressed left ventricular function after an acute myocardial infarction †
Prognostic value of coronary artery calcium screening in asymptomatic smokers and non-smokers by Leslee J. Shaw, Paolo Raggi, Tracy Q. Callister, and Daniel.
Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: A guide to therapeutic decision-making in patients.
Randomized, non-inferiority trial of three limus agent- eluting stents with different polymer coatings: the Intracoronary Stenting and Angiographic Results:
Reduction in recurrent cardiovascular events with prasugrel compared with clopidogrel in patients with acute coronary syndromes from the TRITON-TIMI 38.
High heart rate: a cardiovascular risk factor? by Stéphane Cook, Mario Togni, Marcus C. Schaub, Peter Wenaweser, and Otto M. Hess EHJ Volume 27(20):
Prof. Dr. med. Sigmund Silber Cardiology Practice and Hospital
Figure 1 Flow diagram displaying the proportions of patients with troponin measurements available from all eligible patients and the resulting study population.
Figure 1 Ischaemic endpoints
Figure 1 Patient flow chart.
Figure 2 Kaplan–Meier estimates of event-free survival (survival to the combined endpoint). From: Long-term outcomes of patients with acute myocardial.
Figure 3 One-year adverse events (death, post-discharge myocardial infarction, revascularization) after PCI according to patients who (A) would not have.
The European Society of Cardiology Presented by Dr. Bo Lagerqvist
Copyright © 2009 American Medical Association. All rights reserved.
CHD-related catheterization
Contemporary Diagnosis and Management of Unstable Angina
The following slides are based on a presentation at a Satellite Symposium in association with the Annual Cardiovascular Conference at Lake Louise, Alberta,
% Heparin + GPI IIb/IIIa Bivalirudin +
The European Society of Cardiology Presented by RJ De Winter
Risk Stratification in Non-ST-segment Elevation Acute Coronary Syndromes: Troponin Alone Is not Enough  Philippe Gabriel Steg, Gordon FitzGerald, Keith.
Global Registry of Acute Coronary Events: GRACE
OASIS-5: Study Design Randomize N=20,078 Enoxaparin (N=10,021)
Figure 1 Design of trials included in individual patient data meta-analysis. Unless provided in the caption above, the following copyright applies to the.
Major bleeding with bivalirudin versus unfractionated heparin (UFH) in predominantly ST segment elevation myocardial infarction (STEMI) studies; (A) glycoprotein.
Major bleeding with bivalirudin versus unfractionated heparin (UFH) in predominantly non-ST segment elevation acute coronary syndrome (NSTE-ACS) studies;
Use of evidence-based cardiac medications before, during and after hospitalisation for the index event in (A) overall ACS population and (B) patients with.
Presentation transcript:

Guidelines for the diagnosis and treatment of non-ST- segment elevation acute coronary syndromes by Jean-Pierre Bassand, Christian W. Hamm, Diego Ardissino, Eric Boersma, Andrzej Budaj, Francisco Fernández-Avilés, Keith A.A. Fox, David Hasdai, E. Magnus Ohman, Lars Wallentin, William Wijns, Alec Vahanian, John Camm, Raffaele De Caterina, Veronica Dean, Kenneth Dickstein, Gerasimos Filippatos, Steen Dalby Kristensen, Petr Widimsky, Keith McGregor, Udo Sechtem, Michal Tendera, Irene Hellemans, José Luis Zamorano Gomez, Sigmund Silber, Christian Funck-Brentano, Steen Dalby Kristensen, Felicita Andreotti, Werner Benzer, Michel Bertrand, Amadeo Betriu, Raffaele De Caterina, Johan DeSutter, Volkmar Falk, Antonio Fernandez Ortiz, Anselm Gitt, Yonathan Hasin, Kurt Huber, Ran Kornowski, Jose Lopez- Sendon, Joao Morais, Jan Erik Nordrehaug, Sigmund Silber, Philippe Gabriel Steg, Kristian Thygesen, Marco Tubaro, Alexander G.G. Turpie, Freek Verheugt, and Stephan Windecker EHJ Volume (): June 14, 2007 © The European Society of Cardiology All rights reserved. For Permissions, please

The spectrum of acute coronary syndromes. Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Example of release of cardiac markers in a patient with non-ST-elevation acute coronary syndrome (shaded area indicates normal range). Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Death, myocardial infarction, and major bleeds at the completion of study medication in randomized trials of unfractionated heparin/low molecular weight heparin (filled bars) vs. control (open bars). Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Death, myocardial infarction, and major bleeds at 30 days in randomized trials of enoxaparin (filled bars) vs. unfractionated heparin (open bars). Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Death, myocardial infarction, and major bleeds at 30 days in randomized trials of direct thrombin inhibitors (filled bars) vs. unfractionated heparin/low molecular weight heparin (open bars). Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Death, myocardial infarction, and major bleeds at the end of study medication in four randomized trials of aspirin (filled bars) vs. control (open bars). Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Death, myocardial infarction, and major bleeds at 30 days in randomized trials of glycoprotein IIb/IIIa inhibitors (filled bars) vs. control (open bars) in a conservative strategy. Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Death or myocardial infarction in six contemporary randomized trials comparing early invasive (filled bars) vs. conservative strategy (open bars). Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

The ability to demonstrate relative mortality benefit with the revascularization strategy depends on the gradient in rates of revascularization between both randomization arms. Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Kernel curves of in-hospital mortality (black) or bleeding (grey) according to the level of creatinine clearance in patients treated with unfractionated heparin (plain curves) and low molecular weight heparin (dashed curves). Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Clinical outcomes for patients stratified by age (invasive vs. conservative strategies) from the TACTICS–TIMI-18 trial.420 Reproduced with permission. Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Treatment effect on 30-day mortality among diabetic patients with non-ST-elevation acute coronary syndrome from six randomized clinical trials.233 Reproduced with permission. Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Hospital outcomes according to degree of renal function impairment for the subgroup of patients with non-ST-elevation myocardial infarction/unstable angina from the GRACE registry.460 Heart 2003;89:1003–1008, reproduced with permission from the BMJ Publishing Group. *P < 0.05 across all categories of renal function within the non-ST-elevation myocardial infarction/unstable angina subgroup. **P < across all categories of renal function within the non-ST-elevation myocardial infarction/unstable angina subgroup. Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please

Decision-making algorithm for the management of patients with non-ST-elevation acute coronary syndrome. Jean-Pierre Bassand et al. Eur Heart J 2007;eurheartj.ehm161 © The European Society of Cardiology All rights reserved. For Permissions, please