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Prediction of fatal or near-fatal cardiac arrhythmia events in patients with depressed left ventricular function after an acute myocardial infarction †

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Presentation on theme: "Prediction of fatal or near-fatal cardiac arrhythmia events in patients with depressed left ventricular function after an acute myocardial infarction †"— Presentation transcript:

1 Prediction of fatal or near-fatal cardiac arrhythmia events in patients with depressed left ventricular function after an acute myocardial infarction † by Heikki V. Huikuri, M.J. Pekka Raatikainen, Rikke Moerch-Joergensen, Juha Hartikainen, Vesa Virtanen, Jean Boland, Olli Anttonen, Nis Hoest, Lucas V.A. Boersma, Eivind S. Platou, Marc D. Messier, and Poul-Erik BlochThomsen EHJ Volume (): January 20, 2009 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

2 Study Flow Chart. *Major reasons for exclusions from the study were refusal of the patient or the attending physician treating the patient for participation in the study (n = 380), the inability of the patient to participate in the study due to other serious illness (n = 312), planned coronary bypass graft surgery (n = 184) or death (n = 89) before the implantation of a loop-recorder and/or the risk stratification tests. Heikki V. Huikuri et al. Eur Heart J 2009;eurheartj.ehn537 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

3 Clinical presentation, type of documented arrhythmia, and the mode of documentation of primary endpoints. Heikki V. Huikuri et al. Eur Heart J 2009;eurheartj.ehn537 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

4 Adjusted hazard ratios (HR) with 95% confidence intervals of the variables as predictors of primary endpoint. Heikki V. Huikuri et al. Eur Heart J 2009;eurheartj.ehn537 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

5 Kaplan–Meier estimate of the time from MI to primary endpoint, stratified by inducible sustained monomorphic ventricular tachycardia (MMVT) (panel A) and by reduced very-low frequency spectral component (VLF) of heart rate variability (panel B). Heikki V. Huikuri et al. Eur Heart J 2009;eurheartj.ehn537 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org


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