By: Dan Tamayo.  Electrospun Nanofibers are polymer solutions that are pumped through a syringe  They form an ultrafine fiber that are layered on top.

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Presentation transcript:

By: Dan Tamayo

 Electrospun Nanofibers are polymer solutions that are pumped through a syringe  They form an ultrafine fiber that are layered on top of each other to form a mesh  This mesh can be used to culture and cultivate cells as a scaffold in tissue engineering

fundamentals-optimizing-solution-and-apparatus- parametershttp:// fundamentals-optimizing-solution-and-apparatus- parameters 2:23

 Used for tissue engineering scaffolding  Can be used to deliver medication

 Electrospinning was first discovered by Marley and Cooley  The apparatus was designed and patented  The design was perfected and a new apparatus was patented, this is the apparatus and technique we use today

 Today there are ways that nanofibers can be electrospun while infused with medication. While these nanofibers biodegrade, the medication is evenly released throughout the body.

 Research  Difficult to do

 We will be able to make scaffolding out of materials and chemicals that mimic human proteins and tissues identically.  The optimal scaffold will be found to make cells grow, mature and direct cell migration to the best of their ability.

 Meng, Z & Zu, X (2011) Preparation and characterization of electrospun PLGA/gelatin nanofibers as a potential drug delivery system. Colloids and Surfaces B: Biointerfaces. 84 (1)  Chinwe Nwachukwu, C (2010) Electrospinning protein nanofibers to control cell adhesion. University of South Florida Scholar Commons. 55 (3)  Subbiah, h & Bhat, G (2005) Electrospinning of nanofibers. Applied Polymer Science. 96 (2)