Chronic Hemodialysis Catheters  In site greater than 3 weeks  Tunneled under the skin  Attached felt cuff  Indicated for acute, chronic hemodialysis, apheresis and infusion

 QUINTON PermCath  Silicone; Flow Rates 300ml/min - 380ml/min  MAHARKAR 13.5 Fr  Silicone; Flow Rates 300ml/min - 380ml/min  MAHARKAR MAXID Dual Lumen  Proprietary Polyurethane; Flow Rates up to 450ml/min  TANDEM-CATH Catheter System  Proprietary Polyurethane; Flow Rates up to 400ml/min Chronic Hemodialysis Catheters Tyco Healthcare Chronic Catheters

Tyco Healthcare Portfolio Tyco New:MAXID & TANDEM CATH New: TANDEM CATH Tyco MAHURKAR 13.5 PERMCATH MAHURKAR 13.5 PERMCATH New:MAXID

Chronic Hemodialysis Catheters QUINTON PERMCATH

Benefits  Biocompatibility  Will not breakdown over time  Maximizes flow at low pressure  Round lumens provide efficient flow dynamics  Minimizes recirculation Chronic Hemodialysis Catheters QUINTON PERMCARTH Clinical Performance Features  Silicone Material  “Shot Gun” Lumen Design  Staggered Tip Design

Features  Color Coded Ultem Adapters  Clear Silicone Extensions  Durable Inline Clamps Benefits  Damage resistant  Ease of Use  Do not crimp with repeated use  Ensures secure/ready available closure of extensions Chronic Hemodialysis Catheters QUINTON PERMCARTH Safety & Reliability

Features  Suture Wings:  Widely spaced  Low profile  Transparent  Thick Felt Cuff Benefits  Reduces risk of infection  Facilitates skin inspection  Easy to clean  Keeps catheter in place  Reduces infection  Promotes good tissue in growth Chronic Hemodialysis Catheters QUINTON PERMCARTH Safety & Reliability (cont.)

Features  Minimal Side Holes  Repair Kit Benefits  Minimizes clotting  Saves cost & reduces patient trauma Chronic Hemodialysis Catheters QUINTON PERMCARTH Safety & Reliability (cont.)

Features  Printed Priming Volumes  Radiopaque Benefits  Allows for easy visualization of priming volumes for user.  Facilitates quick visualization under X-Ray/fluoroscopy Chronic Hemodialysis Catheters QUINTON PERMCARTH Ease of Use

Chronic Hemodialysis Catheters Mahurkar 13.5

Features  Double “D” Lumen Design  Silicone material  Variety of lengths (4)  Staggered Tip Chronic Hemodialysis Catheters Mahurkar 13.5 Benefits  Maximum flow with low pressure  Biocompatibility  Will not breakdown over time  Fits all size patients  Minimize recirculation Clinical Performance

Features  Color Coded Ultem Adapters  Clear Silicone Extensions  Durable Inline Clamps Benefits  Damage resistant  Ease of Use  Do not crimp with repeated use  Ensures secure/ready available closure of extensions Chronic Hemodialysis Catheters Mahurkar 13.5 Safety & Reliability

Features  Suture Wings:  Widely spaced  Low profile  Transparent  Thick Felt Cuff Benefits  Reduces risk of infection  Facilitates skin inspection  Easy to clean  Keeps catheter in place  Reduces infection  Promotes good tissue in growth Chronic Hemodialysis Catheters Mahurkar 13.5 Safety & Reliability (cont.)

Features  Minimal Side Holes  Repair Kit Benefits  Minimizes clotting  Saves cost & reduces patient trauma Chronic Hemodialysis Catheters Mahurkar 13.5 Safety & Reliability (cont.)

Features  Printed Priming Volumes  Radiopaque Benefits  Allows for easy visualization of priming volumes for user.  Facilitates quick visualization under X-Ray/fluoroscopy Chronic Hemodialysis Catheters Mahurkar 13.5 Ease of Use

Chronic Hemodialysis Catheters Mahurkar MAXID

DESCRIPTION  Chronic-Cuffed (Long-term)  Double “D” Lumen  14.5 Fr. OD  Proprietary Polyurethane  Performance  High Flow (450ml/min)  Kink Resistance

Features  Proprietary Polyurethane Catheter Material  Double "D" Design Benefits  Facilitates percutaneous placement & resists collapse during treatment  Superior kink resistance  Stands up to standard cleansing with PVD – Iodine and Others  Most efficient flow to pressure ratios for polyurethane catheters Chronic Hemodialysis Catheters Mahurkar MAXID Clinical Performance

Features  14.5Fr Outer Diameter  Staggered Tip Benefits  Provides high flows (up to 450ml/min) at low venous and arterial pressures  Low recirculation rate Chronic Hemodialysis Catheters Mahurkar MAXID Clinical Performance (cont.)

Features  Two Side Hole Configurations:  with side holes  without side holes  Transparent Suture Wings  Straight or Curved Silicone Extensions Benefits  Provides choice of design  May enhance patency and minimize clothing  Facilitates skin inspection  Minimizes risk of exit site infection  Increases patient comfort  Allows for numerous insertion sites  Do not crimp with repeated clamping Chronic Hemodialysis Catheters Mahurkar MAXID Safety & Reliability

Features  Durable inline clamps  Thick Felt Cuff  Ultem Adapters Benefits  Ensures secure/readily available closure of extensions  Keeps catheter in place  Reduces infection  Promotes good tissue in growth  Lightweight, durable, and damage resistant Chronic Hemodialysis Catheters Mahurkar MAXID Safety & Reliability (cont.)

Features  Radiopaque  Printed Priming Volumes  StatLock Device Benefits  Facilitates quick visualization under X- Ray/fluoroscopy  Easy maintenance; easy visualization for user  Secures catheter without sutures, may reduce infection Chronic Hemodialysis Catheters Mahurkar MAXID Ease of Use

Features  Variety of Lengths & tip-to-cuff distances  New Tunneler Benefits  Aids in securing the proper catheter for diverse patient sizes  Formable for flexibility in technique  Atraumatic tip and back end minimizes trauma  Easy to grip for ease of insertion Chronic Hemodialysis Catheters Mahurkar MAXID Ease of Use (cont.)

 Two (2) 10Fr independent catheters  Attachable extensions Chronic Hemodialysis Catheters TANDEM-CATH

Features  Proprietary Polyurethane Catheter Material  10 Fr Circular Lumen Design  Individual Tip Placement Benefits  Facilitates percutaneous placement & resists collapse during treatment  Superior kink resistance  Stands up to standard cleansing with PVPI and others  Provides large ID for flows up to 400ml/min. at low arterial and venous pressures  Ability to technically place catheter tips as desired to minimize and optimize flow rates Chronic Hemodialysis Catheters TANDEM-CATH Clinical Performance

Features  Dual Catheters Benefits  Allows for flexible placement  Allows for reverse tunneling  Access flexibility for unique patients  Allows single or dual site insertion  Allows customization of catheter length Chronic Hemodialysis Catheters TANDEM-CATH Clinical Performance (cont.)

Chronic Hemodialysis Catheters TANDEM-CATH Safety & Reliability Features  Two Side Hole Configurations:  with side holes  without side holes Benefits  Provides choice of design  May enhance patency and minimize clotting

Chronic Hemodialysis Catheters TANDEM-CATH Safety & Reliability (cont.) Features  Suture Wing & STATLOCK  Ultem Adapters Benefits  part of the connector housing assembly  Suture holes are small and located on opposite sides of the connector  Statlock securement device locks the catheter in place & minimizes risk of exit site infection  Light weight, durable, and damage resistant

Chronic Hemodialysis Catheters TANDEM-CATH Safety & Reliability (cont.) Features  Radiopaque  Durable inline clamps  Silicone Extensions Benefits  Facilitates quick visualization under x-ray/fluoroscopy  Ensures secure/readily available closure of extensions  Will not crimp over time  Able to visualize fluids

Chronic Hemodialysis Catheters TANDEM-CATH Safety & Reliability (cont.) Features  Thick Felt Cuff  Repair Kit Benefits  Keeps catheter in place  Reduces infection  Promotes good tissue ingrowth  Extension repair kit avoids patient trauma and cost of another surgical procedure. Can typically be done at the bedside. Repair kit is improved over TESIO with silicone extensions vs. polyurethane

Features  StatLock Device  10 Fr Dilator/Sheath  Printed Priming Volumes Benefits  Secures catheter without sutures, may reduce infection  Minimizes overall insertion hole by 0.5Fr vs. the competition  Easy Maintenance Chronic Hemodialysis Catheters TANDEM-CATH Ease of Use

Features  Back-end Assembly Benefits  2-piece assembly vs. 3 pieces of competitor Chronic Hemodialysis Catheters TANDEM-CATH Ease of Use (cont.) TESIO IFU (3- Piece Assembly) TANDEM-CATH IFU (2-Piece Assembly)

Features  C-Clamps Benefits  4 C-clamps in the kit to allow a secure and REMOVABLE clamping and unclamping during each step of assembly Chronic Hemodialysis Catheters TANDEM-CATH Ease of Use (cont.) TESIO IFU (Assembly) TANDEM-CATH IFU (Assembly w/ C-Clamp) Hands- free “C- clamp”

Features  Variety of Lengths & tip-to-cuff distances  New Tunneler Benefits  Aids in securing the proper catheter for diverse patient sizes  Formable for flexibility in technique  Atraumatic tip and back end minimizes trauma  Easy to grip for ease of insertion Chronic Hemodialysis Catheters TANDEM-CATH Ease of Use (cont.)