Ciprofloxacin Inhibition of Experimental Fracture-Healing* by P. M. HUDDLESTON, J. M. STECKELBERG, A. D. HANSSEN, M. S. ROUSE, M. E. BOLANDER, and R. PATEL.

Slides:

Advertisements

Similar presentations

Healing of a Critical-Sized Defect in the Rat Femur with Use of a Vascularized Periosteal Flap, a Biodegradable Matrix, and Bone Morphogenetic Protein.

Advertisements

Periprosthetic Humeral Fractures After Shoulder Arthroplasty by Sanjay Kumar, John W. Sperling, George H. Haidukewych, and Robert H. Cofield J Bone Joint.

Fixation of the Coronoid Process in Elbow Fracture- Dislocations by Grant E. Garrigues, Walter H. Wray, Anneluuk L.C. Lindenhovius, David C. Ring, and.

Radiographic and Histologic Assessment of Calcium Sulfate in Experimental Animal Models and Clinical Use as a Resorbable Bone-Graft Substitute, a Bone-Graft.

Biomechanical and Histological Evaluation of a Calcium Phosphate Cement* by ELIZABETH P. FRAKENBURG, STEVEN A. GOLDSTEIN, THOMAS W. BAUER, SCOTT A. HARRIS,

Regeneration of Meniscal Cartilage with Use of a Collagen Scaffold. Analysis of Preliminary Data* by KEVIN R. STONE, J. RICHARD STEADMAN, WILLIAM G. RODKEY,

The Effects of Simulated Transverse, Anterior Column, and Posterior Column Fractures of the Acetabulum on the Stability of the Hip Joint* by MARK S. VRAHAS,

Distal Radial Fractures in Older Men by Carl M. Harper, Shannon K. Fitzpatrick, David Zurakowski, and Tamara D. Rozental J Bone Joint Surg Am Volume 96(21):

Avoiding Complications in the Treatment of Humeral Fractures by Jeffrey O. Anglen, Michael T. Archdeacon, Lisa K. Cannada, and Dolfi Herscovici J Bone.

Morbid Obesity: A Significant Risk Factor for Failure of Two-Stage Revision Total Hip Arthroplasty for Infection by Matthew T. Houdek, Eric R. Wagner,

The AOA-JOA 2014 Exchange Traveling Fellowship: Banzai and Beyond by Wakenda K. Tyler, Hassan R. Mir, Dan A. Zlotolow, and Leo T. Kroonen J Bone Joint.

Evaluation of Articular Cartilage Progenitor Cells for the Repair of Articular Defects in an Equine Model by David D. Frisbie, Helen E. McCarthy, Charles.

Surgical Anatomy of the Supraclavicular Brachial Plexus by Sophia Leung, Dan A. Zlotolow, Scott H. Kozin, and Joshua M. Abzug J Bone Joint Surg Am Volume.

RhBMP-2/Calcium Phosphate Matrix Accelerates Osteotomy-Site Healing in a Nonhuman Primate Model at Multiple Treatment Times and Concentrations by Howard.

Total Knee Arthroplasty with Retention of Both Cruciate Ligaments. A Nine to Eleven-Year Follow-up Study* by J.-M. CLOUTIER, P. SABOURET, and A. DEGHRAR.

Scoliosis in Patients with Duchenne Muscular Dystrophy by Lori A. Karol J Bone Joint Surg Am Volume 89(suppl 1): February 1, 2007 ©2007 by The Journal.

The Effect of Implants Loaded with Autologous Mesenchymal Stem Cells on the Healing of Canine Segmental Bone Defects* by SCOTT P. BRUDER, KARL H. KRAUS,

Symposium - The Outcomes Movement in Orthopaedic Surgery: Where We Are and Where We Should Go by MARC F. SWIONTKOWSKI, JOSEPH A. BUCKWALTER, ROBERT B.

Long-Term Outcomes of Lumbar Posterior Apophyseal End-Plate Lesions in Children and Adolescents by Kosaku Higashino, Koichi Sairyo, Shinsuke Katoh, Shyoichiro.

Relationship Between Rates and Outcomes of Operative Treatment for Lumbar Disc Herniation and Spinal Stenosis by ROBERT B. KELLER, STEVEN J. ATLAS, DAVID.

Extracellular Matrix Bioscaffolds for Orthopaedic Applications by Jolene E. Valentin, John S. Badylak, George P. McCabe, and Stephen F. Badylak J Bone.

The Osteoinductivity of Silicate-Substituted Calcium Phosphate by Melanie J. Coathup, Sorousheh Samizadeh, Yvette S. Fang, Thomas Buckland, Karin A. Hing,

Allograft-Prosthesis Composite for Revision of Catastrophic Failure of Total Elbow Arthroplasty by Pierre Mansat, Robert A. Adams, and Bernard F. Morrey.

Histological Changes in the Human Anterior Cruciate Ligament After Rupture* by M. M. Murray, S. D. Martin, T. L. Martin, and M. Spector J Bone Joint Surg.

Development of a Patient-Reported Measure of Function of the Knee* by JAMES J. IRRGANG, LYNN SNYDER-MACKLER, ROBERT S. WAINNER, FREDDIE H. FU, and CHRISTOPHER.

Osteosarcoma Arising from Heterotopic Ossification After an Electrical Burn. A Case Report* by ALBERT J. ABOULAFIA, FLEMING BROOKS, JOANNE PIRATZKY, and.

Mechanotransduction and Fracture Repair by Elise F. Morgan, Ryan E. Gleason, Lauren N. M. Hayward, Pui L. Leong, and Kristy T. Salisbury Palomares J Bone.

Tibial Tubercle-Trochlear Groove Distance: Defining Normal in a Pediatric Population by Aaron J. Dickens, Nathan T. Morrell, Andrew Doering, Dan Tandberg,

An MBA: The Utility and Effect on Physicians' Careers by Selene G. Parekh, and Bikramjit Singh J Bone Joint Surg Am Volume 89(2): February 1, 2007.

N-Acetylcysteine Inhibits Post-Impact Chondrocyte Death in Osteochondral Explants by James A. Martin, Daniel McCabe, Morgan Walter, Joseph A. Buckwalter,

Risk of Injury to the Superior Gluteal Nerve When Using a Proximal Incision for Insertion of a Piriformis-Entry Reamed Femoral Intramedullary Nail by Jason.

The Financial Impact of Orthopaedic Fellowship Training by Trevor Gaskill, Chad Cook, James Nunley, and R. Chad Mather J Bone Joint Surg Am Volume 91(7):

Pulmonary Effects of Fixation of a Fracture with a Plate Compared with Intramedullary Nailing. A Canine Model of Fat Embolism and Fracture Fixation* by.

Dose and Time-Dependent Effects of Cyclooxygenase-2 Inhibition on Fracture-Healing by Ann Marie Simon, and J. Patrick O'Connor J Bone Joint Surg Am Volume.

Natural History of Early Onset Scoliosis by Pedro Fernandes, and Stuart L. Weinstein J Bone Joint Surg Am Volume 89(suppl 1):21-33 February 1, 2007 ©2007.

Nicotine Delays Tendon-to-Bone Healing in a Rat Shoulder Model by L.M. Galatz, M.J. Silva, S.Y. Rothermich, M.A. Zaegel, N. Havlioglu, and S. Thomopoulos.

Anabolic Steroids Reduce Muscle Damage Caused by Rotator Cuff Tendon Release in an Experimental Study in Rabbits by C. Gerber, D.C. Meyer, K.M. Nuss, and.

Total Knee Arthroplasty in Patients with Ankylosing Spondylitis by Javad Parvizi, Gavan P. Duffy, and Robert T. Trousdale J Bone Joint Surg Am Volume 83(9):

Severe Acute Respiratory Syndrome (SARS) in a Geriatric Patient with a Hip Fracture by Kwok Chuen Wong, Kwok Sui Leung, and Mamie Hui J Bone Joint Surg.

The Trends in Treatment of Femoral Neck Fractures in the Medicare Population from 1991 to 2008 by Benjamin J. Miller, Xin Lu, and Peter Cram J Bone Joint.

Vancomycin-Modified Implant Surface Inhibits Biofilm Formation and Supports Bone-Healing in an Infected Osteotomy Model in Sheep by Suzanne Stewart, Stephanie.

by James H. Dubberley, Kenneth J. Faber, Joy C. MacDermid, Stuart D

Reconstruction of Segmental Bone Defects Due to Chronic Osteomyelitis with Use of an External Fixator and an Intramedullary Nail by Levent Eralp, Mehmet.

Consequences of Oversizing: Nerve-to-Nerve Tube Diameter Mismatch by Jonathan Isaacs, Satya Mallu, Wo Yan, and Barrett Little J Bone Joint Surg Am Volume.

Ilizarov Hip Reconstruction for the Late Sequelae of Infantile Hip Infection by S. Robert Rozbruch, Dror Paley, Anil Bhave, and John E. Herzenberg J Bone.

Intraosseous Injection of rhBMP-2/Calcium Phosphate Matrix Improves Bone Structure and Strength in the Proximal Aspect of the Femur in Chronic Ovariectomized.

A Granulomatous Mass Surrounding a Maverick Total Disc Replacement Causing Iliac Vein Occlusion and Spinal Stenosis by Michael R. Berry, Brian G. Peterson,

Effect of Short-Duration Low-Magnitude Cyclic Loading Versus Immobilization on Tendon-Bone Healing After ACL Reconstruction in a Rat Model by Robert H.

Unusual Osteochondroma of the Medial Part of the Clavicle Causing Subclavian Vein Thrombosis and Brachial Plexopathy by Anthony V. Mollano, Mark L. Hagy,

Morphology of the Bursae Associated with the Greater Trochanter of the Femur by Stephanie J. Woodley, Susan R. Mercer, and Helen D. Nicholson J Bone Joint.

Management of Capsular Deficiency of the Shoulder by Jon J.P. Warner, Andreas A. Venegas, Janne T. Lehtinen, and John J. Macy J Bone Joint Surg Am Volume.

Characterization and Comparison of Wear Debris from Failed Total Hip Implants of Different Types* by KAZUO HIRAKAWA, THOMAS W. BAUER, BERNARD N. STULBERG,

Variability in Spine Surgery Procedures Performed During Orthopaedic and Neurological Surgery Residency Training by Alan H. Daniels, Christopher P. Ames,

The Influence of Active Shear or Compressive Motion on Fracture-Healing* by SANG-HYUN PARK, KIM O'CONNOR, HARRY MCKELLOP, and AUGUSTO SARMIENTO J Bone.

Lower-Extremity Peripheral Nerve Blocks in the Perioperative Pain Management of Orthopaedic Patients by Benjamin E. Stein, Umasuthan Srikumaran, Eric W.

A Dynamic Study of Thoracolumbar Burst Fractures by Ruth K. Wilcox, Thomas O. Boerger, David J. Allen, David C. Barton, David Limb, Robert A. Dickson,

Microcomputed Tomography Characterization of Shoulder Osseous Deformity After Brachial Plexus Birth Palsy: A Rat Model Study by Zhongyu Li, Jonathan Barnwell,

Curvature and Range of Motion of the Cervical Spine After Laminaplasty* by Ikuo Aita, Yasuyoshi Wadano, and Takeshi Yabuki J Bone Joint Surg Am Volume.

Pirogoff Amputation for Foot Trauma: An Unusual Amputation Level by F.M. den Bakker, H.R. Holtslag, and J.G.H. van den Brand J Bone Joint Surg Am Volume.

The Clamshell Osteotomy: A New Technique to Correct Complex Diaphyseal Malunions by George V. Russell, Matt L. Graves, Michael T. Archdeacon, David P.

Enhanced Fracture and Soft-Tissue Healing by Means of Anabolic Dietary Supplementation by Michael S. Hughes, Peter Kazmier, Timothy A. Burd, Jeff Anglen,

Ultrasound Measurements of Torsions in the Tibia and Femur by David Hudson, Todd Royer, and James Richards J Bone Joint Surg Am Volume 88(1): January.

Temporary Internal Distraction as an Aid to Correction of Severe Scoliosis by Jacob M. Buchowski, David L. Skaggs, and Paul D. Sponseller JBJS Essent Surg.

The Need for Increased Access to the U.S. Health-Care System by Jesse E. Bible, Richard S. Lee, and Gary E. Friedlaender J Bone Joint Surg Am Volume 91(2):

An AOA Critical Issue: Aging of the North American Population: New Challenges for Orthopaedics* by Joseph A. Buckwalter, James D. Heckman, and David P.

Calcifying Fibrous Pseudotumor. A Case Report* by HIROSHI ORUI, MITSUNORI YAMAKAWA, AKIRA ISHIKAWA, and TOSHIHIKO OGINO J Bone Joint Surg Am Volume 80(4):

Dynamic Hip Screw Compared with External Fixation for Treatment of Osteoporotic Pertrochanteric Fractures by Antonio Moroni, Cesare Faldini, Francesco.

Effect of Cultured Autologous Chondrocytes on Repair of Chondral Defects in a Canine Model* by HOWARD A. BREINAN, TOM MINAS, HU-PING HSU, STEFAN NEHRER,

Matrix Metalloproteinase-9 Induces the Formation of Cartilage Canals in the Chondroepiphysis of the Neonatal Rabbit by Joel Thomas Kirk Melton, Nicholas.

Topical Cutaneous CO 2 Application by Means of a Novel Hydrogel Accelerates Fracture Repair in Rats by Takaaki Koga, Takahiro Niikura, Sang Yang Lee, Etsuko.

Presentation transcript:

Ciprofloxacin Inhibition of Experimental Fracture-Healing* by P. M. HUDDLESTON, J. M. STECKELBERG, A. D. HANSSEN, M. S. ROUSE, M. E. BOLANDER, and R. PATEL J Bone Joint Surg Am Volume 82(2): February 1, 2000 ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 1-A Histological appearance of the fracture callus from a control rat after four weeks of healing. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 1-B Histological appearance of the fracture callus from a control rat after four weeks of healing. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 2-A Histological appearance of the fracture callus from a ciprofloxacin-treated rat after four weeks of healing. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 2-B Histological appearance of the fracture callus from a ciprofloxacin-treated rat after four weeks of healing. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 3 High-magnification photomicrographs showing the histological appearance of the endochondral ossification front in calluses from control (A) and ciprofloxacin-treated (B) animals. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 4 High-magnification photomicrographs showing the morphology of the chondrocytes at the endochondral ossification front in calluses from control (A) and ciprofloxacin-treated (B and C) animals. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 5 High-magnification photomicrographs showing the trabecular structure at the endochondral ossification front in calluses from control (A) and ciprofloxacin-treated (B and C) animals. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 6-A Histological appearance of areas of cystic degeneration seen at a distance from the fracture callus in specimens from the ciprofloxacin-treated rats. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 6-B Histological appearance of areas of cystic degeneration seen at a distance from the fracture callus in specimens from the ciprofloxacin-treated rats. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 7-A Ultrastructural appearance of chondrocytes and surrounding matrix in the fracture callus of control (Fig. 7-A) and ciprofloxacin-treated (Fig. 7-B) rats after four weeks of healing. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.

Fig. 7-B Ultrastructural appearance of chondrocytes and surrounding matrix in the fracture callus of control (Fig. 7-A) and ciprofloxacin-treated (Fig. 7-B) rats after four weeks of healing. P. M. HUDDLESTON et al. J Bone Joint Surg Am 2000;82: ©2000 by The Journal of Bone and Joint Surgery, Inc.