ALCOHOL Chapter 8. PRODUCTION OF ALCOHOL Anaerobic condition CO 2 Glucose Pyruvate Acetaldehyde Fermentation of yeast Fermentation of yeast.

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Presentation transcript:

ALCOHOL Chapter 8

PRODUCTION OF ALCOHOL Anaerobic condition CO 2 Glucose Pyruvate Acetaldehyde Fermentation of yeast Fermentation of yeast

PRODUCTION OF ALCOHOL Acetaldehyde NADH NAD + Ethanol

ENERGY CONTENT OF COMMON ALCOHOLIC BEVERAGES

Alcohol Metabolism

DIGESTION AND ABSORPTION OF ALCOHOL No digestion required Absorbed by simple diffusion and moves directly into blood stream No specific mechanism required to enter body cells Alcohol damages cell membrane proteins as it enters body cells.

ALCOHOL METABOLISM

Catalase Found in the liver Minor pathway for alcohol metabolism Catalase H 2 O 2 H 2 O Ethanol Acetaldehyde

What to do with Acetaldehyde? Acetaldehyde dehydrogenase Acetyl CoA is non-toxic to body cells

Fate of Acetyl-CoA CO 2 + H2O Acetyl-CoAFatty Acid Glucose

Moderate Alcohol Consumption Versus Alcohol Abuse Benefits and Problems

Problems Associated with Alcohol Abuse Increases 5 of the top 10 causes of death in the U.S. Cirrhosis of the liver Inflammation of stomach and pancreas Hypertension and hemorrhagic stroke

Problems Associated with Alcohol Abuse Brain damage and neurotransmitter imbalances Myocardial depression and Arrhythmias Cardiomyopathy Fetal Alcohol Syndrome

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