National Heart, Lung, and Blood Institute Cancer Research Opportunities Liana Harvath, NHLBI U.S. Department of Health and Human Services National Institutes.

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Presentation transcript:

National Heart, Lung, and Blood Institute Cancer Research Opportunities Liana Harvath, NHLBI U.S. Department of Health and Human Services National Institutes of Health National Heart, Lung, and Blood Institute

Stem Cell Transplantation Stem Cell Sources –Cord blood –Bone marrow –Peripheral blood transplantation –Ex vivo expansion Immune Reconstitution

Transfusion Medicine and Cellular Therapies - Dendritic cell vaccines - Plasmid DNA cell priming - T-cell adoptive immune therapy - Blood product usage - Hematopoietic growth factors

Stem Cell Biology Novel Approaches to Enhance Animal Stem Cell Research [PA ] –For R01 or R21 grants Human Embryonic Stem Cell Research –Competitive supplements [PAR ] –Training initiatives –Infrastructure enhancement awards

Thrombosis and Cancer Role of platelets/activated platelets in tumor growth, metastasis and angiogenesis Procoagulant and angiogenic properties of tumor cells Role of fibrinolytic and coagulation proteins in tumor growth and metastasis

Pre-Cancerous Conditions Mechanisms involving susceptibility to cancer in pre-cancerous conditions such as: –Myelodysplastic Syndromes & Myeloproliferative Disorders –Fanconi Anemia –Diamond Blackfan Anemia Drug-induced carcinogenesis of the blood.

Contact Information Liana Harvath, Ph.D. Deputy Director Division of Blood Diseases and Resources NHLBI, NIH Bethesda, MD Phone: FAX:

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