Cancer MITOSIS GONE WILD!

Cells division is … The multiplying of cells through mitosis resulting in generation after generation of identical daughter cells. The daughter cells receive exact copies of the parent cell’s DNA.

Why do we need cell division? Allows us to grow Allows us to heal and repair ourselves Even allows us to reproduce

The Reasons for Cancer Cancer occurs when: the rate of cell division goes out of control. Mutations occur in the genes that control cell division. Mutations are cells with changes to their DNA. A Carcinogen is any chemical or energy that causes a mutation in DNA.

The Reasons for Cancer Cancer cells reproduce in defiance of the normal restraints: They don’t stop at the checkpoints in the cell cycle They lack cell-to-cell communication ability They resist to cell “suicide” signals

Images of Cancer The following slides include images of advanced stages of different cancers. The images may be somewhat disturbing, so if you are squeamish, you may want to cover your eyes.

Skin Cancer

Lung Cancer

Brain Cancer

Oral Cancer

Tumor on Spleen

Causes for Cancerous Mutations Viruses some viruses interfere with cell division by inserting their own DNA Radiation high energy radiation like ultraviolet light, X-rays and Gamma rays have been linked to forms of cancer Chemicals - cigarette smoke and smog have been linked to lung cancer

Tumour Terms A tumour is a mass of disfunctional cells that have a grown from mutant parents. Benign tumours: mainly harmless Cells remain clustered together. Malignant tumours: can be deadly. Parts of these tumors can break off and spread throughout your body (metastasis).

Cancer Treatments Or a combination of all 3. 1. Surgery: tumour is cut out. 2. Radiation Therapy: radiation is used to kill the tumour cells 3. Chemo Therapy: Toxic chemicals attempt to poison the cancer cells (stop mitosis). Or a combination of all 3.

Reflect On Your Learning Produce a K-Q-L chart for this lesson in your notes. KNEW QUESTIONS LEARNED Identify 2-3 things from the lesson that you already knew Identify 2-3 questions that you now have about the lesson Identify 2-3 things that you learned about during the lesson

Video Animations Oncogenes Angiogenesis and Metastasis