Astrix Technology Group Global Solutions Provider To The Regulated Community Implementing Business Logic Within A LIMS To Reduce Manual Data Review And Increase Productivity Robert D. Walla Presented At EAS 2005 Somerset, NJ

Typical Benefits Of LIMS  Increases Individual And Organizational Efficiency  Increases Quality By Eliminating Manual Data Entry and Resulting Transcription Errors  Facilitates Access To Data Across The Enterprise  Decreases Costs Astrix Technology Group

Typical LIMS Functionality  Data Storage Client Information Client Information Sample Receipt Data Sample Receipt Data Analytical Data Analytical Data  Sample Scheduling  Sample Tracking  Report Production  Financial Tracking Astrix Technology Group

Current Value Proposition Current Uses Of LIMS Provide Automation In Only Portions Of The Sample Process “Incremental Results” Astrix Technology Group

A New Paradigm Progressive Organizations Incorporate Business Logic Into The LIMS To Automate The Entire Sample Analysis And Reporting Process Astrix Technology Group

LIMS Business Logic  Automatic Evaluation Of Results To Determine Sample “Rechecks”  Comparison Of Results To Industry Standards – Automatic Recommendations  Automatic Interpretation Of Results and Reporting Astrix Technology Group

The Oil Analysis Laboratory processes 700,000 per year. A LIMS was used to schedule samples and store results however each sample was manually reviewed to assure accuracy of results and incorporate specific interpretation comments. The Laboratory Needed To Modify The Work Process To Keep Up With The Increase Sample Load. Case Study Client: Global Lubricants Company Project Overview:

Case Study Global Lubricants Company Laboratory Analysis  Viscosity  Wear Metals  Contaminants Fuel Anti-Freeze (Glycol) Water Dirt (Silicon) Soot

Global Lubricants Company Manual Data Review Process

Case Study Global Lubricants Company Laboratory Manual Review Process Analytical Data Evaluation The process of reviewing the data of each sample to assure that the quality control parameters are within specifications and the data is consistent with historical results. Data Interpretation The process of comparing the sample data to OEM specifications, determining the severity of the variance and making recommendations to the client.

Case Study Global Lubricants Company Analytical Data Evaluation Process Quality Control Sample Evaluate the QC sample to assure that it is within specification. Reanalyze batch is outside limits. Historical Results Compare results to historical values. Reanalyze samples if results are inconsistent. Compare Results To Other Tests Compare results to the results of other tests to identify inconsistencies. For example, a high Sodium value is indicative of antifreeze contamination. If the sample is negative for antifreeze it will be reanalyzed to verify the result.

Case Study Global Lubricants Company Data Interpretation Process Compare Results To OEM Specification Values are compared to OEM specifications based on make, model, product and age of lubricant Assign Severity Codes Severity codes are assigned to each test based on the variance from the OEM specifications Recommendations Provide clients with recommendations for addressing issues identified by the sample analysis

Case Study Global Lubricants Company Metrics – Manual Process  Process 685,000 Samples Per Year  Required 4 full time employees to review data  Average Turnaround Time = 2.21 days  Cost Per Sample = $4.47

Case Study Global Lubricants Company LIMS Upgrade  Incorporated Data Evaluation Logic Into LIMS  Incorporated Data Interpretation Logic Into LIMS  Recommendation Added To The Reports  Incorporated Logic For Manual Review  Reports Automatically Sent To Client

Global Lubricants Company Automated Data Review Process

Case Study Global Lubricants Company Metrics – Automated Process  Process 730,000 Samples Per Year  Required 1 full time employee to review data  Average Turnaround Time = 1.49 days  Cost Per Sample = $3. 98

Benefits Of Incorporating Business Logic Into LIMS Astrix Technology Group  Reduce Sample Turnaround Time  Reduce Costs  Increase Consistency Of Results

Robert D. Walla ( 732) Astrix Technology Group Questions Or Comments:

Astrix Technology Group Global Solutions Provider To The Regulated Community