Esophagus: Normal Lower Esophageal and Squamo- columnar Junction Mucosae.

Slides:



Advertisements
Similar presentations
FISIOLOGIA DIGESTIVA (BCM II) Clase 3: Fisiopatología Esofágica Dr. Michel Baró Aliste.
Advertisements

Gastrointestinal System
GI System: Esophagus & Stomach Laboratory Orientation.
Histology for Pathology Gastrointestinal System and Exocrine Pancreas
University of California, San Francisco
Infectious Esophagitis Immunocompromised Host -Steroids, Chemo/Rad therapy, AIDS, Transplant patients Endoscopic Appearance Location - Often more proximal.
GENERAL THORACIC SURGERY CHAPTER 141
Esophagus Anatomy, Physiology, and Diseases
Dysphagia Dr. Raid Jastania.
8 LECTURES Gastro-esophageal reflux disease Peptic Ulcer Disease
DIGESTIVE. ESOPHAGUS Stratified squamous epithelium Submucosa The muscularis externa Esophageal glands.
Slide 155, pharynx, H&E, 4x obj. mucosal epithelium lamina propria
GastroEsophageal Reflux Disease (GERD)
GASTROINTESTINAL PATHOLOGY LAB I January 10, 2013.
Overview: Evaluation of the Gastrointestinal Tract
Gastroesophageal Reflux Disease: Diagnosis and Investigations
Gastrointestinal Diseases Dr. Maha Arafah Pathology, 2013.
Gastroesophageal Reflux Disease (GERD)
Inflammation to Cancer: GERD & Barrett’s Esophagus Elevating Healthcare to a New Level MNDAKSPAN Fall Conference Kim A. Noble, Ph.D., RN, CPAN
TISSUES CH. 4: THE FABRIC OF LIFE. TISSUE TYPES Epithelial tissue Covers Connective tissue Supports Muscle tissue Moves Nervous tissue Controls.
Upper Gastrointestinal Diseases. Upper GI Diseases Esophagus Stomach Duodenum.
GASTROINTESTINAL TRACT. A 40 yr old man complains of difficulty of swallowing & a tendency to regurgitate his food
Case 519: 63 y/o man with long standing heart burn and progressive dysphagia.
Sarah Coyan/Emma Cressey
Gastrointestinal system Part II The oesophagus. A muscular tube Conduction of food and drink Sphincters at top and bottom.

Esophagus cancer Dr Sanei Associated professor of pathology GI and Liver patholoogist.
Gastrointestinal Diseases Dr. Maha Arafah Pathology, 2012.
8 LECTURES Gastro-esophageal reflux disease Peptic Ulcer Disease Inflammatory bowel disease-1 Malabsorption Diarrhea Colonic polyps and carcinoma-1 Inflammatory.

The Role of Secondary Versus Tertiary Prevention in Decreasing the Incidence of Esophageal Adenocarcinoma in Patients with Barrett’s Esophagus Lindsay.
HISTOLOGY OF ESOPHAGUS &gastro esophageal junction
Diseases of the Oropharynx and Esophagus November 19, 2007 NCDD Meeting Chair: P. Jay Pasricha, MD Vice Chair: David A. Lieberman, MD.
Gastroesophageal Reflux Disease PRESONTATION BY MELISSA VANDYKE.
GROUP D.  narrowing of the esophagus(distal) near the junction with the stomach (squamocolumnar jxn).  sequelae of gastroesophageal reflux– induced.
Gastro Esophageal Reflux Disease (GERD)
Reflux Esophagitis and Esophageal Carcinoma Thomas Rosenzweig, MD.
Pathological Diagnosis of Barrett’s Esophagus
Gastroesophageal Reflux Disease ( GERD ) Prof.Dr.Khalid A. Al-Khazraji MBCHB, MD, CAMB, FRCP, FACP
Digestive Disorders Stomach Disorders. ©
Gastroesophageal Reflux Disease (GERD). * Definition: inflammation of the lower part of the esophagus due to abnormal reflux of gastric contents into.
Disorders of the Esophagus
Prof KHALED HEMIDA Ain Shams University. قال الله تعالي : يرفع الله الذين آمنوا منكم و الذين أوتوا العلم درجات. قال رسول الله ( صلي الله عليه و سلم ):
Classification of superficial neoplastic lesion : stomach 소 화 기 내 과 황보 영.
Date of download: 6/28/2016 Copyright © American College of Chest Physicians. All rights reserved. From: Upper Esophageal Sphincter and Gastroesophageal.
The histological structure of the intestine consist of four layers:-
Barrett Esophagus 2008 년도 2 학기 의학과 석. 박사 공통과목 위장관의 외과병리.
Eosinophilic Esophagitis. Case Presentation 35 year old man presented with intermittent upper esophageal dysphagia, mostly with solids for > 5 years.
Gastroesophageal Reflux Disease (GERD)
The Development and Validation of an Endoscopic Grading System for Barrett’s Esophagus The Prague C & M Criteria Gastroenterology 2006;131:1392~1399 This.
Controversies in Barrett Esophagus
The Esophageal Squamous Epithelial Cell—Still a Reasonable Candidate for the Barrett’s Esophagus Cell of Origin?  David H. Wang, MD, PhD  Cellular and.
The Prevalence of and Risk Factors for Barrett Esophagus in a Korean Population - A Nationwide Multicenter Prospective Study - J Clin Gastroenterol 2009.
I. General Description and Considerations
GI Pathology Lab Dr Heyam.
(A) Region of esophagus demonstrating Barrett esophagus: The normal squamous epithelium (left margin of figure) is replaced by specialized columnar epithelium.
Digestive Disorders Stomach Disorders.
Volume 145, Issue 4, Pages (October 2013)
Ampullary Pyloric Gland Adenoma with High-grade Dysplasia (Video)
The emerging role of histologic disease activity assessment in ulcerative colitis  Rish K. Pai, MD, PhD, Vipul Jairath, MD, PhD, Niels Vande Casteele,
Elizabeth Montgomery, Marcia Irene Canto 
Gastrointestinal Pathology I
Volume 117, Issue 1, Pages (July 1999)
Gastro-Esophageal Reflux Disease (GERD)
Aspiration Pneumonia and Related Syndromes
GERD and Peptic ulcer Lab
Controversies in Barrett Esophagus
Presentation transcript:

Esophagus: Normal Lower Esophageal and Squamo- columnar Junction Mucosae

Esophagus: Normal Squamous Epithelium

Esophagus: Normal Squamo- columnar Junction

Esophagitis (Inflammation and Reactive Epithelial Changes of the Esophageal Mucosa) Has Many Causes

Reflux Esophagitis is the Culmination of Gastro-Esophageal Reflux-Induced Changes in Epithelial Cell Turnover

Esophagus: G-E Reflux - Changes in Epithelium and Vascular Papillae

Esophagus: G-E Reflux - Defenses Against Reflux-induced Injury

Esophagus: G-E Reflux - Symptoms and Endoscopic Findings in Reflux are NOT Predictive of Biopsy Findings

Esophagus: G-E Reflux - Heightened Epithelial Turnover in G-E Reflux is Shown by Increased Epithelial Tritiated Thymidine Labeling

Esophagus: G-E Reflux - Reflux- induced Epithelial Change Is a Consequence Of Increased Cell Turnover

Acute (Neutrophilic) Inflammation and Erosion In Severe Reflux Esophagitis

Severe Epithelial Reactive Changes with Eosinophils (EOS) in Gastroesophageal Reflux

Sequelae Of Prolonged G-E Reflux

Barrett’s Esophagus: Development And Anatomic Relationships

Endoscopic Landmarks In The GEJ Region: Normal Versus Barrett’s (Columnar-lined) Esophagus With Location Of Lower Esophageal Sphincter (LES)

Requirements For Diagnosis Of Barrett’s Esophagus

Barrett’s Esophagus: Gross Appearance

Barrett’s Esophagus Should Be Suspected And Confirmed By Biopsy When The Squamo- columnar Junction Is Displaced Or Highly Irregular

Barrett’s Mucosa (BM) With Submucosal Esophageal Gland (SMEG) Below Muscularis Mucosae (MM)

Barrett’s Mucosa: Distinctive (Specialized) Type