1. GI System: Esophagus & Stomach Laboratory Orientation

2. #126 H&E Mid-esophagus Muscularis Externa Skeletal muscle Mixed smooth and skeletal muscle Submucosal sero- mucous gland Muscularis mucosae Lamina propria

3. #126 Esophagus Also #153 Muscularis mucose Submucosal gland

4. Muscularis Externa of mid-esophagus (#126): Skeletal and smooth m. Muscularis Externa of lower esophagus (#155): Smooth muscle only

6. #155 : Cardiac Stomach Cardio-esophageal junction (arrow) Cardiac glands

7. #156: Fundic Stomach Rugae

8. Mucosa of the Fundic Stomach Lymphatic nodule Muscularis mucosae

9. #156, #157: Gastric glands Gastric pit lined by surface mucous cells Mucous neck cells Fundus or body

10. #157: Body of the gastric glands

11. #157: Base of the gastric glands Chief cells Parietal cells

12. #162 Pylolic Stomach Pylo-duodenal junction (arrow) Pyloric sphincter muscle Duodenum

13. Cardiac glands: coiled (mucous) glands pit:gland=1:1 Fundic (gastric) glands: straight glands pit:gland=1:5 Pyloric glands: coiled (mucous) glands pit:gland=2~3:1

14. GI System: Small and Large Intestine Laboratory Orientation

15. #29 Small Intestine Mesentery (ct + epithelium) Submucosa (connective tissue) Mucosa (epithelium + lamina propria) Muscularis Externa (smooth muscle) Lumen Muscularis mucosae

16. #29 – Intestinal Villi Intestinal villi

17. #29-Simple columnar epithelium with striated border (microvilli) and goblet cells Microvilli (striated border) Goblet cells Enterocytes ?

18. #162 Pylo-duodenal junction (arrow) Pyloric sphincter muscle

19. #161 Pylo-duodenal Junction and Pancreas Pyloric stomach Duodenum Pancreas Duodenum Pancreas Pyloric stomach

20. #161 Muscularis mucosae Lymphatic nodules Brunner’s gland

21. #161, 162 Duodenum Lumen Intestinal villus Muscularis mucosae crypts or i. glands Brunner’s glands pancreas

22. #29, 168 Jejunum or Ileum lumen submucosa Muscularis mucosae Crypts of Lieberkuhn

23. #29, Intestinal glands (crypts) Paneth cells Enteroendocrine cells Mitotic cell ? ? ?

24. #246 UCSF Enteroendocrine cell Paneth cell

25. #29, Myenteric (Auerbach’s) plexus Ganglion cells

26. #176: Colon (Mucosa of the colon) m.m No villi, Straight glands, lots of goblet cells

27. #176 – colon mucosa

28. #177-1, 177-3, 177-2 Recto-anal junction Hemorrhoidal veins Muscularis mucosae Type of epithelium changes Muscularis mucosae frays Dilated veins