, Dear I am writing today as a [mom/dad] of a child with a very complex and obscure disease: tuberous sclerosis complex (TSC). A disease that creates tumors among vital organs, like the heart, brain, lungs, kidneys and liver. A disease that holds an incredible amount of promise for major breakthroughs in cancer, epilepsy and even autism. The back page of this pamphlet provides a bit more detail on how important TSC is to so many scientific breakthroughs. The reason TSC has recently been discovered to be such a lynchpin disease—even though it affects only 50,000 people in our country—is because a group of committed moms and dads, brothers and sisters, and friends and neighbors kept fighting until the world began to notice. Ours is a true American grassroots success story. We formed our own organization, the TS Alliance. We lobby congress. We spend countless hours working with doctors and scientists to make sure TSC is on their radar screen. We help educators know how to work with our children. We take care of each other. We also raise all our own money. One parent, one donor, one handshake at a time. The biggest tool we have to raise the funds is our community walkathon, Step Forward to Cure TSC, and that is why I am writing. To ask for nothing more than a bit of help by [running some of our PSA Radio Spots/TV Spots/Print Ads/Banner Ads] [placing some of our posters and flyers in your facility] and, whenever possible, talking about our Step Forward to Cure TSC walkathon here in on ! As you can see on the following pages, we can provide as many different tools as you can help us with, in whatever format you need. I’d also be happy to chat at your convenience to answer any questions you may have. Thank you so much for your consideration of my request, Phone:

30-SECOND RADIO Tuberous sclerosis complex is a genetic disease that can cause brain tumors, epilepsy, autism, kidney failure. Even death. I’m Julianne Moore. National spokesperson for Step Forward to Cure TSC. A series of community walks to benefit the Tuberous Sclerosis Alliance. People from all walks of life are Stepping Forward to Cure TSC. So dust off your sneakers. And see when there’s a walk near you at Step-Forward-to-Cure-TSC-dot-org. 60-SECOND RADIO Tuberous sclerosis complex is a genetic disease that can cause brain tumors, epilepsy, autism, kidney failure. Even death. I’m Julianne Moore. National spokesperson for Step Forward to Cure TSC. A series of local fundraising walks to benefit the Tuberous Sclerosis Alliance. The TS Alliance is a small but determined group of people who are trying desperately to fund research that will finally break the back of this linchpin disease. Doctors and researchers. Moms and dads. Aunts and uncles. Sisters and brothers. Grandparents and friends. People who have tuberous sclerosis complex. People who don’t. [Beat] People like you. [Beat] So whether you walk, donate, volunteer, or all three, Step Forward to Cure TSC. To see when there’s a walk near you, visit Step-Forward- to-Cure-TSC-dot-org. Radio & TV PSAs with Julianne Moore We are so lucky to have Julianne’s support! We have very effective radio spots that announce our Walkathon, and radio and TV spots that speak about TSC itself. Print/Banner Ads Response to these ads has been 3 to 4 times the average for the media in which they’ve run—a testimony to their human appeal! Walkathon Brochures We can provide the copies—we just need your help to get it in as many hands as possible! Posters People have responded wonderfully to these posters wherever they are on display. Proprietors have noted that their customers truly appreciate their willingness to help. Our Step Forward to Cure TSC Walk-a-thon is on, at ! Anything you could do to help our cause would be deeply appreciated! Our local Step Forward to Cure TSC walkathon is on at ! Anything you could do to help our cause would be deeply appreciated!