Introduction to the NIH Grants System Division of Cancer Biology Introduction to the NIH Grants System New Grantee Workshop, 2014

Organization and Budget The National Institutes of Health: Grants Process Basics The National Cancer Institute: Organization and Budget Scientific & Grants Management Personnel You Should Know The Division of Cancer Biology: Organization and Programmatic Roles

Organization and Budget The National Institutes of Health: Grants Process Basics The National Cancer Institute: Organization and Budget Scientific & Grants Management Personnel You Should Know The Division of Cancer Biology: Organization and Programmatic Roles

NIH is an agency within the U. S NIH is an agency within the U.S. Department of Health and Human Services (DHHS) Administration for Children and Families (ACF) Food and Drug Administration (FDA) Health Resources and Services (HRSA) The Secretary Administration on Aging (AoA) Centers for Medicare and Medicaid Services (CMS) Indian Health Services (IHS) Centers for Disease Control and Prevention (CDC) Substance Abuse and Mental Health Services (SAMHSA) Agency for Toxic Substances and Disease Registry (ATSDR) Agency for Healthcare Research and Quality (AHRQ) National Institutes of Health (NIH) (~$987 Billion) Kathleen Sebelius (~$30 Billion) Source: http://www.hhs.gov/budget

The National Institutes of Health Source: http://www.nih.gov Office of the Director ANIA NIAID NEI NIDCDIDCD NHGRI NIAMS NIDCR NIEHS NIGMS NINDS NINRNINR NCATS NCMHD CC CIT NIDCR (Angela Ng)

The NIH Grant Application Cycle Center for Scientific Review Investigator Initiates Research Idea Assign to SS Assign to Institute Submits Application to NIH Study Section Review for Scientific Merit Institute Office Of Grants Administration Evaluate for Relevance Advisory Councils and Boards Conducts Research Allocates Funds Recommends Action Institute Director Takes Action

Appropriations: Funding The NIH Appropriations Subcommittee on Labor, Health & Human Services, Education and Related Agencies + The NIH budget is specified by Congress through a yearly appropriations bill which is signed into law by the President. Provides each IC with specific funds to carry out their respective programs and missions. Source: http://opa.faseb.org/pages/Publications/washingtonupdate.htm

Appropriations Timeline: The Fiscal Year begins October 1 Congressional Revision & Approval Planning Presentation Execution Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec FY2013 FY2014

NIH Budget Allocation by Institute/Center FY2013 NIH Total = $29.9 Billion Fundable Range = 9th Success Rate = 14.6% NCI 16.4% NIAID 14.5% NHLBI 9.9% NIGMS Payline = 10th Success Rate = 15.9% 7.8%

Organization and Budget The National Institutes of Health: Grants Process Basics The National Cancer Institute: Organization and Budget Scientific & Grants Management Personnel You Should Know The Division of Cancer Biology: Organization and Programmatic Roles

The National Cancer Institute ● Intramural Program Research in NCI laboratories. ● Extramural Program Supports the research of non-Federal scientists in universities, medical schools, hospitals, and research institutions throughout the country and abroad. Source: http://www.cancer.gov/researchandfunding

National Cancer Institute Budget Allocation Research Project Grants 42.8% >80% goes to the Extramural Community in Research Grants, Contracts, Training and Career Development Other Mechanisms 12.5% Intramural Research 16.5% R&D Contracts 11.6% Clinical Cooperative Groups 4.8% Research Career Program 1.5% SPOREs & Other Specialized Centers 6.3% Cancer Centers 5.5%

NCI Organizations Funding/Supporting Extramural Research Divisions Offices/Centers Center for Bioinformatics Division of Cancer Biology Division of Cancer Control and Population Sciences Office of Grants Administration (Brett Hodgkins) Office of Cancer Complementary and Alternative Medicine Division of Cancer Prevention Division of Cancer Treatment and Diagnosis Center to Reduce Cancer Health Disparities (Mary Ann Van Duyn) Center for Cancer Training (Ming Lei) Division of Extramural Activities Small Business Innovation Research Development Center Center for Cancer Genomics Center for Strategic Scientific Initiatives Center for Global Health

Budget and Organization The National Institutes of Health: Grants Process Basics The National Cancer Institute: Budget and Organization Scientific & Grants Management Personnel You Should Know The Division of Cancer Biology: Organization and Programmatic Roles

The NIH Grant Application Cycle Center for Scientific Review Investigator Initiates Research Idea Assign to SS Assign to Institute Submits Application to NIH Study Section: SRO Review for Scientific Merit Institute: Program Director Grants Management Specialist Evaluate for Relevance Advisory Councils and Boards Allocates Funds Recommends Action Institute Director Takes Action

Scientific and Grants Management Personnel Scientific Review Officer (NIH): Responsible for the scientific/technical review of applications Program Director (NCI): Responsible for the scientific and programmatic aspects of a grant Grants Management Specialist (NCI): Responsible for ensuring that all business management actions are performed by the grantee and the NCI in a timely and appropriate manner

Organization and Budget The National Institutes of Health: Grants Process Basics The National Cancer Institute: Organization and Budget Scientific & Grants Management Personnel You Should Know The Division of Cancer Biology: Organization and Programmatic Roles

https://dcb.nci.nih.gov

The Division of Cancer Biology (DCB) supports and facilitates basic research in all areas of cancer biology at academic institutions and research foundations across the United States and abroad. The mission of the DCB is to ensure continuity and stability in basic cancer research while encouraging and facilitating the emergence of new ideas, concepts, and technologies.

Acting Chief: Dan Gallahan, Ph.D. Chief: Jennifer Couch, Ph.D. Chief: Barbara Spalholz, Ph.D. Judy Mietz, Ph.D. Allan Mufson, Ph.D. Suresh Mohla, Ph.D. *Mouse Models of Human Cancer Consortium *Integrative Cancer Biology Program *Tumor Microenvironment Network

What are the key responsibilities of a Program Director? Serve as a liaison between the scientific community and the NCI Serve as a steward of federal funds

What do Program Directors do? I. Pre-Award Phase: Advise scientists on grant applications Attend study section reviews Advise applicants on summary statements and resubmissions Resolve issues on scientific overlap, budget, human/animal subjects and other IRG concerns, foreign applications/foreign components Manage appeals Work with grants management specialists on making awards

What do Program Directors do? II. Post-Award Phase: Monitor progress of research grants Review and approve annual progress reports Report major advances to NCI/NIH leadership Identify gaps/needs/opportunities in the cancer research arena Monitor compliance of regulations, policies, special terms of the award Contact point for requests of administrative supplement funding (Elisa Woodhouse)

Introduction to the NIH Grants System Division of Cancer Biology The End Introduction to the NIH Grants System