1. Introduction to the NIH
Introduction to the NIH Grants System
Introduction to the NIH
Grants System
Welcome. Over the next few minutes I’ve been asked to provide a brief orientation of the NIH grants system…so I’ll be introducing some of the main topics--the details of which will be further flushed out in talks you’ll hear later today and tomorrow.
New Grantee Workshop, 2010

2. The National Institutes of Health: The National Cancer Institute:
Grants Process Basics
The National Cancer Institute:
Budget and Organization
Scientific and Grants Management Personnel You Should Know
I’ll focus on three themes, an overview of the NIH, how the NCI is organized and how their budgets are determined and allocated, and lastly I’ll introduce the scientific and grants management people who intersect with your grants and yourselves at various stages. And they’ll be talking to you in more detail about what they do and how their work effects you later today and tomorrow. The goal is to give you a better sense of where your grants and your research fit into the big picture and help you better navigate the NIH grants system.
I’ll focus on three themes: First, an overview of the NIH and the grants process basics; Second how the NCI organized and operates to fund cancer research; Lastly, I’ll introduce the scientific and grants management people who intersect with your grants and yourselves at various stages. And they’ll be talking to you in more detail about what they do and how their work effects you later today and tomorrow. The goal is to give you a better sense of where your grants and your research fit into the big picture and help you better navigate the NIH grants system.
New Grantee Workshop, 2010

3. The National Institutes of Health: Grants Process Basics
The National Cancer Institute: Budget and Organization
Scientific and Grants Management Personnel You Should Know
New Grantee Workshop, 2009

4. NIH is an agency within the U. S
NIH is an agency within the U.S. Department of Health and Human Services
Administration for
Children and Families
(ACF)
Food and Drug
Administration
(FDA)
Health Resources
and Services
(HRSA)
The Secretary
Administration on
Aging
(AoA)
Centers for Medicare and Medicaid Services
(CMS)
Indian Health
Services
(IHS)
Centers for
Disease Control
and Prevention
(CDC)
Substance Abuse and
Mental Health Services
(SAMHSA)
Agency for Toxic
Substances and
Disease Registry
(ATSDR)
Agency for
Healthcare Research
and Quality (AHRQ)
National Institutes
of Health
(NIH)
Kathleen Sebelius
The Department of Health and Human Services consists of the Office of the Secretary and 11 operating divisions.. The Department of Health and Human Services (HHS) is the United States government's principal agency for protecting the health of all Americans and providing essential human services, especially for those who are least able to help themselves.  The NIH is the flagship agency of the HHS public health system dedicated to improving health through medical research
The work of HHS is conducted by the Office of the Secretary and 11 agencies. The agencies perform a wide variety of tasks and services, including research, public health, food and drug safety, grants and other funding, health insurance, and many others.
With over 300 programs valued at approximately $698 billion, HHS’ mission includes a wide range of human issues,
including substance abuse, Medicare and Medicaid, children’s health, health disparities, disease prevention and health promotion.
Source:

5. The National Institutes of Health
Source:
Office of the Director
ANIA
NIAID
NEI
NIDCDIDCD
NHGRI
NIAMS
NIDCR
NIEHS
NIGMS
NINDS
NINRNINR
NCRR
NCMHD CC
CIT
NIDCR
The NIH consists of the Office of the Director and 27 other components: 19 Institutes (outlined in blue) and 7 Centers (outlined in green) and the National Library of Medicine, collectively the Institutes and Centers are referred to as ICs, and are largely organized by disease focus such as Cancer, Aging, Heart/Lung/Blood, etc., and most of these fund scientific research specific to their mission. There are a few Center that do not fund research and are defined by their activity such as the Center for Scientific Review.
The majority grant applications submitted to the NIH for consideration for funding by any funding Institute or Center are sent to the Center for Scientific Review, and this is the first step in the NIH Grants Cycle………….

6. The NIH Grant Application Cycle
Center for Scientific Review
Investigator
Initiates
Research Idea
Assign to SS
Assign to Institute
Submits
Application
to NIH
Study Section
Review for Scientific Merit
Institute
Grants
Management
Office
Evaluate for Relevance
Advisory Councils and Boards
Conducts
Research
Allocates
Funds
Recommends Action
Institute Director
Takes Action

7. Appropriations: Funding The NIH+
The NIH budget is specified by Congress through a yearly appropriations bill which is signed into law by the President and provides each IC with specific funds to carry-out their respective programs and missions.
The funds to support NIH-sponsored research is specified by Congress in a yearly appropriations bill, which is signed in to law by the president and provides each Institute with specific funds to carry out their respective programs and missions. The appropriations bill that’s important for funding the NIH is the Labor, Health and Human Services, Education and Related Agencies.
And it’s the role of each Institute to select the most meritorious applications and ensure the funds are well spent.
Source:

8. Appropriations Timeline: The Fiscal Year begins October 1
Continuing
Resolution
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
Jan
FY2010
FY2011
Its important to know that our fiscal year begins on October 1; the orange indicates today’s date—so we’re near the end of FY2008 and waiting for next year’s budget—and the new budget will determine next year’s funding plan (the percentage of grant applications that can be funded and what level existing grants get funded).
However, the appropriations bill is seldom passed on time and usually takes Congress and the President some months to iron out budget wrinkles. During that interim period, Congress usually enacts a continuing resolution that funds the NIH at previous years level to continue its operations. Under a CR the NCI can only fund a limited number of new grant awards. NCI may fund existing awards at a reduced level until the budget passes but these are restored once the budget is passed.

9. The National Institutes of Health:
Grants Process Basics
The National Cancer Institute: Budget and Organization
Scientific and Grants Management Personnel You Should Know

10. NIH Gets 1% of U.S. Budget
$3.55 Trillion
$30.8
Bill.

11. NIH Budget Allocation by Institute
FY2010
NIH Total = $30.8 Billion
NCI
($5.15 Billion)

12. The National Cancer Institute
● Intramural Program
Research in NIH laboratories.
● Extramural Program
Supports the research of non-Federal scientists in universities, medical schools, hospitals, and research institutions throughout the country and abroad.
Each IC, and we’re focused on the NCI as a representative institute, pursues its mission by conducting research at the NIH through an intramural program and by sponsoring research at universities through an extramural program.
Source:

13. National Cancer Institute Budget
Allocation
Cancer
Control 11%
Other 12%
Training 4%
Groups 3%
Support 6%
Research 9%
SPOREs 3%
Cancer Centers 6%
Research Project Grants (RPG) 44%
Intramural
>80% goes to the Extramural
Community in Research Grants, Contracts, Training
and Career Development
Over 80% of the NCI budget goes to support the Extramural Community in funding for Research Grants, Contracts, Training and Career Development. The majority of the NCI budget supports the what’s called the RPG pool composed of grants which comprise, among other mechanisms, the R01, R21, P01 and R00 awards that most are familiar with.

14. NCI Organizations Funding/Supporting Extramural Research
Division of Cancer Biology Division of Cancer Control and Population Sciences Division of Cancer Prevention Division of Cancer Treatment and Diagnosis Division of Extramural Activities
Center for Bioinformatics Center to Reduce Cancer Health Disparities Office of Cancer Complementary and Alternative Medicine (OCCAM) Office of Technology and Industrial Relations

15. *Mouse Models of Human Cancer Consortium
*Integrative Cancer Biology Program
*Tumor Microenvironment Network
Chief:
Don Blair, Ph.D.
Jennifer Couch, Ph.D.
Chief: Barbara
Spalholz, Ph.D.
Judy Mietz, Ph.D.
Allan Mufson, Ph.D.
Suresh Mohla, Ph.D.

16. https//dcb.nci.nih.gov

17. The National Institutes of Health: Grants Process Basics
The National Cancer Institute: Organization, Budget and Culture
Scientific and Grants Management Personnel You Should Know
I’ll focus on three themes: First, an overview of the NIH and the grants process basics; Second how the NCI organized and operates to fund cancer research; and lastly, I’ll introduce the scientific and grants management people who intersect with your grants and yourselves at various stages of the grants process and they’ll be talking to you in more detail about what they do and how their work effects you later today and tomorrow. The goal is to give you a better sense of where your grants and your research fit into the big picture and help you better navigate the NIH.

18. The NIH Grant Application Cycle
Center for Scientific Review
Investigator
Initiates
Research Idea
Assign to IRG
Assign to Institute
Submits
Application
to NIH
Study Section: SRO
Review for Scientific Merit
Institute: Program Directors
Grants
Management
Specialist
Evaluate for Relevance
Advisory Councils and Boards
Allocates Funds
Recommends Action
Institute Director
Takes Action

19. Scientific and Grants Management Personnel
Scientific Review Officer:
Responsible to the NIH for the scientific/technical review of applications
Program Director:
Responsible to the NIH for scientific and programmatic aspects of a grant
Grants Management Officer/Specialist:
Responsible for ensuring that all business management actions are performed by the grantee and the NIH in a timely and appropriate manner

20. Introduction to the NIH
Introduction to the NIH Grants System
The End
Introduction to the NIH
Grants System
Welcome. Over the next few minutes I’ve been asked to provide a brief orientation of the NIH grants system…so I’ll be introducing some of the main topics--the details of which will be further flushed out in talks you’ll hear later today and tomorrow.
New Grantee Workshop, 2010

21.
Source: