Methadone By: Heidi Smith

Drug Name Information  Street Names  Brand Name  Chemical Name Frizzies Dollies Dolophine Methadone Hydrochloride

Action of the Drug  Attaches to opioid receptors in the brain  Attaches to spinal column  Attaches to peripheral tissues and organs  All to help limit pain and limit anxiety

Medical Use  Methadone is used as a pain reliever and as part of drug addiction detoxification.  Methadone is available in:  Tablets  oral solution (liquid)  an injection

History Of Methadone  synthesized during World War II  Discovered in Germany in the late 1930’s  Approved in 1947 in the United States used primarily as a treatment for narcotic addictions, primarily heroin  Methadone was soon found to have a much longer effect than morphine drugs, it's effects lasting up to 24 hours.

Schedule Rating Schedule Rating  Schedule II  high potential for abuse  Abuse of the drug or other substance may lead to severe psychological or physical dependence.

Physiological Effects  Dry Mouth  Constipation  Respiratory depression  Muscle Flaccidity  Decreased heart rate

Psychological Effects Psychological Effects  Dizziness  Mood Swings  Depressed reflexes  Altered sensory perception

Possible Side Effects  Loss of appetite, nausea/vomiting  Poor blood circulation  Back and joint aches  Skin rashes  Aching muscles and joints  Irregular periods

Bibliography     gs/methadone.htm gs/methadone.htm gs/methadone.htm 