Bioinformatics Stephen Voglewede

What is Bioinformatics Computers have changed a lot of fields – including biology

Bioinformatics? Sequence analysis Evolutionary mapping Modeling of biological systems

Algorithms and Tools Needleman-Wunsch UCSC Bioinformatics Website, NCBI BLAST, Genome Browser

Current Research Vijay Pande: David Baker: Foldit Still looking for UCSC candidate Areas of interest: structural elucidation, information systems for drug testing

What is your approach Bioinformatics Textbook from Prof. Khuri’s class: pretty useful overview Plenty of resources for Human Genome Project Pour through research papers for Needleman- Wunsch and for current research – access issue might need to be addressed

What will be your final product? Report containing the following: Brief overview of history of bioinformatics Description of some of the algorithms commonly used Walkthrough of some of the tools available to for public use Brief overview of some of the more interesting research in Bioinformatics right now