Fluorescein Angiography & OCT in Diabetic Retinopathy بسم الله الرحمن الرحيم Fluorescein Angiography & OCT in Diabetic Retinopathy F. Kianersi M.D 1388 / 11 / 30

Fluorescein Angiography Hyper-Fluorescence Hypo-Fluorescence

Hyper - Fluorescence Into Tissue (Staining) Window Defect RPE Atrophy (Laser Schar) Anomalous Vessels Dilation and Beading of Retinal Veins Intraretinal Microvascular Abnormalities (IRMA) NVE – NVD – FPE – FPD Leakage Into Tissue (Staining) In a Preformed Space (Pooling)

Hypo - Fluorescence Vascular Filling Defect Nerve Fiber Layer Infarcts (Cotton-Wool Spots) Arteriolar Abnormalities Areas of Capillary Non-Perfusion (CNP) Blockage Pre-Retinal & Vitreous Hemorrhage Intra-Retinal Hemorrhage & Hard Exudates Sub-Retinal Hemorrhage & RPE Hypertrophy

Fluorescein Angiography is a valuable adjunct to diagnosis that supports and enhances, but does not replace, standard Clinical Examination.

One exception to this rule is found in patients with: Dense Asteroid Hyalosis obscuring the Posterior Pole.

Hyper - Fluorescence

Microaneurysms

Microaneurysm

Non-Cystoid Retinal Leakage Microaneurysm Non-Cystoid Retinal Leakage

Focal Cystoid Retinal Leakage

Microaneurysms & Hard Exudates Diffuse Cystoid Retinal Leakage

Cystoid Retinal Leakage

Cystoid Retinal Leakage (CME) (Pooling)

Leakage Into Tissue (Staining)

Dilation and Beading of Retinal Veins & IRMA & CNP

Non-Cystoid Retinal Leakage & NVD

New-Vascularization of Retina (NVE & NVD)

PDR-Large NV & CNP

CNV in PDR

Sub-Macular CNV in PDR

Window Defect of the RPE Photo-Coagulation

Hypo - Fluorescence

Blockage Opacities of the Refractive Media and Vitreous

Blockage Pre-Retinal Hemorrhages

Blockage Pre-Retinal Gliosis and Fibrosis

Blockage Pre-Retinal and Intra-Retinal Gliosis and Fibrosis

Blockage Intra-Retinal Hemorrhages

Blockage Hard Exudates

Blockage RPE Hypertrophy after Photo-Coagulation

Vascular Filling Defect

Vascular Filling Defect Macular Ischemia

Mixed Maculopathy Later frames: Diffuse Leakage. Early frames: Numerous Microaneurysms & CNP. Later frames: Diffuse Leakage.

Vascular Filling Defect Cotton Wool Spot

Capillary Non-Perfusion (CNP) Vascular Filling Defect Capillary Non-Perfusion (CNP)

Vascular Filling Defect CNP

Diabetic Papillophathy

Diabetic Ischemic Optic Neuropathy

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