Helping doctors make better decisions GIDEON Helping doctors make better decisions Background © 2006 GIDEON Informatics, Inc

INFECTIOUS DISEASE IS ...... 342 Diseases 220 240 2,000 269 65 9,979 © 2006 GIDEON Informatics, Inc

Human metapneumovirus infection Coenurosis Echinococcosis - American polycystic Brainerd diarrhea Human metapneumovirus infection Karelian fever Moniliformis moniliformis Flinders Island spotted fever African tick bite fever Dicrocoeliasis Echinostomiasis Lobomycosis Oesophagostomiasis Pogosta disease Gianotti-Crosti syndrome Gastrodiscoidiasis Entomophthoramycosis Linguatulosis Bertielliasis Rocio So, what can you tell us about Ilheus Wesselsbron Ockelbo disease Gongylonemiasis Rickettsia felis infection Astrakhan fever Mammomonogamiasis Pentastomiasis Group C viral fevers Thogoto Hendra virus disease Tanapox virus disease Louping ill Omsk hemorrhagic fever Oropouche Nanophyetiasis Lagochilascariasis Metorchiasis Mayaro Spondweni Whitewater Arroyo virus infection Pythiosis © 2006 GIDEON Informatics, Inc

Diseases discovered by man [which discovered man] in the last three decades. Year Agent Disease 1973 Rotavirus Rotavirus disease 1975 Parvovirus B19 Fifth disease 1976 Cryptosporidium parvum Cryptosporidiosis 1977 Ebola virus Ebola 1977 Legionella pneumophila Legionellosis 1977 Hantavirus Hemorrhagic fevers 1977 Campylobacter jejuni Campylobacteriosis 1980 T-lymphotrophic virus T-cell leukemia 1981 Toxigenic S. aureus Toxic shock syndrome 1982 E. coli O157:H7 Hemorrhagic colitis, HUS 1982 HTLV-II Hairy cell leukemia 1982 Borrelia burgdorferi Lyme disease 1983 HIV AIDS 1983 Helicobacter pylori Peptic ulcer disease 1985 Enterocytozoon bieneusi Microsporidiosis 1986 Cyclospora cayatenensis Cyclosporidiosis 1988 Human Herpes 6 Roseola infantum 1988 Hepatitis E virus Hepatitis E 1989 Ehrlichia chaffeensis Ehrlichiosis 1989 Hepatitis C virus Hepatitis C 1989 Guanarito virus Venezuelan hemorrhagic fever 1992 Bartonella henselae Cat scratch disease 1993 Sin nombre virus Hantavirus pulmonary syndrome 1994 Sabia virus Brazilian hemorrhagic fever 1995 Human herpesvirus 8 Kaposi sarcoma …and then came: hepatitis GB, pteropus lyssavirus, Nipah virus, Flinder’s Island spotted fever, Hendra virus, metorchiasis, Whitwater Arroyo virus, African tick bite fever, Astrakhan fever, Brainerd diarrhea, American polycystic echinococcosis, HMPV, SARS, Banna virus ….. © 2006 GIDEON Informatics, Inc

INFECTIOUS DISEASE IS ...... 342 Diseases 231 Countries 240 2,000 269 65 9,979 © 2006 GIDEON Informatics, Inc

INFECTIOUS DISEASE IS ...... 342 Diseases 231 Countries Diagnostic tools 240 2,000 Pathogens 269 65 9,979 © 2006 GIDEON Informatics, Inc

Elizabethkinga meningoseptica Dysgonomonas mossii Ruminococcus bromii Varibaculum cambriensis Mycobacterium mageritense Kytococcus schroeteri Shuttleworthia satelles Roseburia intestinalis Anaeroglobus germinatus Bifidobacterium scardovii Not to mention… Inquilinus limosus Corynebacterium aurimucosum Lactobacillus fornicalis Streptococcus lutetiensis Dorea longicatena Engerococcus gilvus Enterobacter cowanii Pandoraea norimbergensis Burkholderia ambifaria Mogibacterium neglectum Actinomyces funkei Catenibacterium mitsuokai © 2006 GIDEON Informatics, Inc

INFECTIOUS DISEASE IS ...... 342 Diseases 231 Countries Diagnostic tools 240 2,000 Pathogens 269 Anti-infective drugs 65 Vaccines Trade names 9,979 © 2006 GIDEON Informatics, Inc

and then there were Enfuvirtide Balofloxacin Lumefrantrine Triclabendazole Prulifloxacin Miltefosine Rifaximin Rokitamicin Rufloxacin Isepamicin and then there were Pipeminic acid Miocamycin Clofoctol Ertapenem Secnidazole Flubendazole Tosufloxacin Nitazoxanide Flomoxef Elfornithine Pleconaril Enfuvirtide Ceftazole Flumequine © 2006 GIDEON Informatics, Inc

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Conclusion GIDEON helps doctors make better decisions Sign up for a free trial at: www.GIDEONonline.com © 2006 GIDEON Informatics, Inc