©2013 ei Technologies Ltd.Confidential – please do not I TechUK eitechnologies.co.uk 1 1 World at One As featured in

©2013 ei Technologies Ltd.Confidential – please do not circulate ei Technologies Who we are What we do Why we do it What stage we’re at Things to discuss Q&A / discussion We measure mood 2

©2013 ei Technologies Ltd.Confidential – please do not circulate Our team 3 Management team Healthcare and Business advisors Matt Dobson Co-Founder and CEO Dr Duncan Barclay Co-Founder and CTO David Browning Start-Up Business Prof Mike Catt Scientific + Innovation Dr Tracey Parsons Clinical Psychology Technical team Prof Stephen Cox Speech Recognition Andrea De-Marco Speaker Identification Funding

©2013 ei Technologies Ltd.Confidential – please do not circulate Setting the scene Treatment of depression and anxiety 4 6million people need treatment 900,000 IAPT treatment target ,000 Treated now 80,000 Baseline Source: IAPT three-year report, Nov 2012

©2013 ei Technologies Ltd.Confidential – please do not circulate The need Improve self-awareness of emotions 5 “Complete once a day for 17 weeks...” Impact Reduced efficacy Increased course duration

©2013 ei Technologies Ltd.Confidential – please do not circulate Our solution: Xpression Turbo-charging the mood diary 6

©2013 ei Technologies Ltd.Confidential – please do not circulate Why this might work Consumer driven, evidence-based 7 UK: Mobilephones have reached saturation UK: 60% of mobilephones are smartphones 40% of smartphone users track their health and fitness $1.3Bn Health and Fitness app market $700Mn was invested in smartphone health in H Smartphone trends Persons, J.B., Burns, D.D., & Perloff, J.M. (1988). Predictors of dropout and outcome in cognitive therapy for depression in a private practice setting. Cognitive Therapy Research, 12(6), Neimeyer, R.A., & Feixas, G. (1990). The role of homework and skill acquisition in the outcome of group cognitive therapy for depression. Behavior Therapy, 21, Bryant, M.J., Simons, A.D., & Thase, M.E. (1999). Therapist skill and patient variables in homework compliance: Controlling the uncontrolled variables in cognitive therapy outcome research. Cognitive Therapy and Research, 23(4), Burns, D.D., & Spangler, D.L. (2000). Does psychotherapy homework lead to improvements in depression in cognitive-behavioral therapy or does improvement lead to increased homework compliance? Journal of Consulting and Clinical Psychology, 68(1), Burns, D., & Nolen-Hoeksema, S. (1991). Coping styles, homework compliance, and the effectiveness of cognitive-behavioral therapy. Journal of Consulting and Clinical Psychology, 59(2), Addis, M.E., & Jacobson, N.S. (2000). A closer look at the treatment rationale and homework compliance in cognitive-behavioral therapy for depression. Cognitive Therapy and Research, 24(3), Patient homework and outcomes

©2013 ei Technologies Ltd.Confidential – please do not circulate How patients use our mood app Automated tracking of emotion 8 10:0011:0012:00 Positive emotions Stressful emotions Neutral Example of feedback to patient Tuesday 27 th March 2014 Client: Helena Stujik 10:11am – 10:23am Reason: My boss called me into her office Feeling: I felt tense 11:07am – 11:12am Reason: Presentation to main board with boss Feeling: Out of depth Client: Helena Stujik Example for weekly summary report Monday 26 March Tuesday 27 March Wednesday 28 March Thursday Time Trigger Feeling 09:35 12:43 15:53 No parking space Phone call for husband Drop folder on foot Sickness Annoyed Hurt and anno 10:11 11:07 My boss Presentation with board Tense Out of depth 08:43 13:01 16:27 Queue of traffic Phone call for husband Shouted at secretary Sickness Frustrated Annoyed 08:59TrafficIll How to use itReports generated

©2013 ei Technologies Ltd.Confidential – please do not circulate Current development plans Validate in prevention then move into treatment 9 Prevention study Alpha dev and trial Q2 ‘13Q3 ‘13Q4 ‘13Q1 ‘14Q2 ‘14Q3 ‘14Q4 ‘14 Psychological therapy study Prevention study Patient preference Clinical relevance of information Completeness of information Over 8 weeks Psychological therapy study Outcomes data ̶Equivalence Over 20 weeks Plus previous measures

©2013 ei Technologies Ltd.Confidential – please do not circulate Questions for you Value to stakeholders – Patients – Providers of psychological therapies – Payer of services (GPs, etc) Other applications – Dementia – PTSD – Autism Adoption route – Evidence base required – Key opinion leaders – Patient and patient group involvement – Route to adoption (providers or payers) Concerns – Privacy – Efficacy – Access (ie must have smartphone) Partners – Which partners to work with – How the partnership might work 10 Matt Dobson Co-Founder and CEO Mobile +44(0) Skype matt.dobson.uk Duncan Barclay Co-Founder and CTO Mobile +44(0) Skype duncan.m.barclay