HFD increased the number of ERα-expressing cells.

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HFD increased the number of ERα-expressing cells. HFD increased the number of ERα-expressing cells. A, HFD increased the number of ERα-expressing cells in the ARC, regardless of hormone treatment. This effect of HFD consumption was detected in the medial, but not anterior or posterior, ARC. B, There was a strong trend towards an HFD-induced increase in ERα expression in the medial, but not anterior or posterior, VMH. C, D, HFD increased the number of leptin-sensitive ERα neurons in the VMH, but not in the ARC. *p < 0.05, +p = 0.054, HFD vs STND. Elizabeth P. Bless et al. eneuro 2016;3:ENEURO.0027-16.2016 ©2016 by Society for Neuroscience