Metabolic Alterations as a Signpost to Early Pancreatic Cancer

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Metabolic Alterations as a Signpost to Early Pancreatic Cancer Natalia Khalaf Gastroenterology Volume 156, Issue 6, Pages 1560-1563 (May 2019) DOI: 10.1053/j.gastro.2019.03.028 Copyright © 2019 Terms and Conditions

Figure 1 Earlier detection of pancreatic cancer through enhanced risk assessment and targeted evaluation. In the general population (A), risk prediction models identify individuals at elevated risk for pancreatic cancer (B). The at-risk population is enriched for people with early-stage pancreatic cancer using circulating markers (C) to identify those for targeted imaging to visualize the pancreatic tumor (D). Detection of the tumor is followed by tissue diagnosis and earlier therapeutic intervention with a greater likelihood for cure (E). Chol, cholesterol; CTCs, circulating tumor cells; ctDNA, circulating tumor DNA; miRNA, microRNA; T3cDM, type IIIc diabetes mellitus. Gastroenterology 2019 156, 1560-1563DOI: (10.1053/j.gastro.2019.03.028) Copyright © 2019 Terms and Conditions