1. Volume 141, Issue 1, Pages 16-20 (July 2011)
Fruit, Vegetables, and Folate: Cultivating the Evidence for Cancer Prevention 
Jung Eun Lee 
Gastroenterology 
Volume 141, Issue 1, Pages (July 2011)
DOI: /j.gastro
Copyright © 2011 AGA Institute Terms and Conditions

2. Figure 1
Proposed relationship between folate and development of colorectal neoplasia. Based on epidemiological data and clinical trials, folate may have an anti-cancer benefit early in the colorectal adenoma-carcinoma sequence (eg, during tumor initiation) with diminishing influence as neoplasia progresses. Thus, the reduction in cancer risk is most evident in comparing extremes of folate intake when introduced to a population at an early stage of the adenoma-carcinoma sequence.
Gastroenterology  , 16-20DOI: ( /j.gastro )
Copyright © 2011 AGA Institute Terms and Conditions