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Do Diabetes Drugs Modify the Risk of Pancreatic Cancer?
Yu–Xiao Yang Gastroenterology Volume 137, Issue 2, Pages (August 2009) DOI: /j.gastro Copyright © 2009 AGA Institute Terms and Conditions
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Figure 1 (A) Diabetes mellitus, metformin, exogenous insulin and pancreatic cancer. IGF-I, insulin-like growth factor-I; AMPK, AMP-activated protein kinase. (B) Proposed mechanism of actions of metformin on AMPK and pancreatic cancer. AMPK, AMP-activated protein kinase; mTOR, mammalian target of rapamycin. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2009 AGA Institute Terms and Conditions
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